Training in Laboratory Animal Science - Information and registation
According to the Regulation on the use of animals in research (Norw: “Forskrift om bruk av dyr i forsøk”) everyone involved in planning, performing, taking care of or killing animals must as a minimum fulfill training program in accordance with Appendix E of the regulation. Mattilsynet clearly stated that it is the singel reserchers responsibility to keep his/her CV updated.
The laboratory animal facility at UiB offers 3 courses in Laboratory Animal Science, in accordanse with the demands of Mattilsynet and the Appendix E of the Regulation on the use of animals in research (Norw: “Forskrift om bruk av dyr i forsøk”)
Lab Animal Science at UiB
By implementation of EU directive 2010/63 there will be a new classification system for personnel using animals in research.
Demands to practical skills are only relevant for persons performing procedures on animals (group A).
Persons planning and designing experiments, but do not themselves perform procedures (Group B), must however know how procedures influence animal welfare and research result, but they do not need to demonstrate practical skills.
The EU commission has made a framework for education of persons using animals in research at different levels based on EU directive 2010/63 that you can download here.
Everyone that applies for access to The Animal Facility at UiB must first module 1 of the training (i.e. LAS 301).
To apply for experiments in FOTS or participate in animal experiments you have to complete the whole training program (LAS 301+LAS302 or 303, or a completed FELASA C course from another institution).
If you have training from another country, part of this might be approved, but still you need to go through a training program (including a test) focused on national rules and regulations.
What is Lab Animal Science?
Laboratory Animal Science (LAS) is a multidisciplinary branch of science contributing to humane use of animals and collection of informative, unbiased and reproducible data.
LAS covers regulation, ethics, alternatives to use of animals, properties of the animals themselves, external factors that influence experiments and design and quality control of studies.
Who needs the courses?
Person designing animal studies, performing procedures are caring for research animals mus be trained.
- Persons planning and designing animal studies («function B») must attend education equivalent to LAS 301 AND LAS 302 (rodents, pigs) OR LAS 303 (fish).
- Persons performing procedures («function A») must, in addition to courses mention above work under supervision until they master the procedures they are going to use. Training must be documented.
For certain tasks there might be demands to task specific courses, for example for advanced surgery and anesthesia.
Persons that is only killing animals («function D») must complete LAS 301 and supervised training in the killing methods they are going to apply.
Timing of training in relation to project start
- Theoretical training must be completed before researchers get access to FOTS and and apply for project authorization
- Practical training of new applicants should be as close to project startup as possible to have practical skills fresh in mind and fingers.
When a new project is authorized training documentation is reviewed again in a “project start-up meeting” - to catch up changes since the application was submitted
Requirements for technical skills apply only to those who will perform procedures on animals (Funtiion A, C and D)
Practical training must be directed towards the species and procedures you plan to work with.
The aim of practical training is to get the neccesary knowledge and skills necessary to handle the animal with as little discomfort to the animal as possible, and thereby both prevent trauma for the animal and unwanted variation in research results.
Practical training should be as close to project startup as possible so you have your practical skills fresh in mind.
- Minimum requirements for practical training include
- Safe handling of animals
- Recognize pain and distress in animals
- Humane killing of animals
- Hygiene procedures and use of personal protective equipment
Persons that cannot document practical training must work under supervision until the master skills well enough not to cause unnecessary stress for the animals or anything that can bias the results of the experiments.
Practical training is not a part of LAS 301/302/303
Practical training on rodents is offered at Dyreavdelingen
Practical training on rodents is offered at Dyreavdelingen-UiB 1-1 or in small group (max 5-6)
Restrain of rodents
Blood sampling in rodents
Injection techniques in rodent (im, ip, iv, sc) in rodents
Euthanasia of rodents
Sexing of rodents
Dress code in the animal facility
Anesthesia – safety check of equipment
Preparation for sterile surgery
Training using alternative methods to animals
Training fee is 2000 NOK
Practical training without use of animals is available on our alternative lab.
LAS courses 2022 and registration
- Registration for external participants: Preregistrering for externe deltagere: Preregistration LAS-courses Spring 2022 (uib.no)
- Students and PhD-candidates must register using StudentWeb
7/2-2022 14-16 Welcome and introduction
22/2-2022 12-16 LAS 301 - Euthanasi, HEP, Q&A
24/2-2022 0900-1100 las 301 -Lectures Q&A, introduction to group work
24/2-3/3 Group work
10/3-2022 0900-1000 Exam
LAS 303 (fish module)
10/3-2022 1400-1600 Lectures
17/3-2022 1030-1530 Lectures
18/3-2022 0830-1500 Lectures
21/3-2022 0900-1200 Lectures
21/3-28/3 Group Work
5/4-2022 0900-1000 Exam
LAS 302 (rodent module)
26/4-2022 1200-1600 Lectures
27/4-2022 0830-12030 Lectures
10/5-2022 0900-1000 Exam
Update course in LAS
Everyone involved in animal experiments have to maintain and document competence trough continuous practice and education.
- If you took the basic course before July 1 2015 you should participate in an update course as a new regulation went into force from that day
- Dyreavdelingen organizes update courses in LAS, see Updated Course in LAS
- Next course is planned in january 2022 (12 for rodents, 13 for fish) - you can register here
Courses outside Norway
Credits for courses
From 2016 courses get new course codes and study-credits.
LAS 301 (before 201): 6 stp
LAS 302/303 (before 202/203): 4 stp
Course fee 2022
The course fee for 2020 is 5500 NOK per course.
Procedure specific training - Surgery
In the case that an experiements include surgery - the reseracher must be specifically trained for these.
Training that must be documentet include:
- Understanding the relevance and need for pre-operative assessment and conditioning.
- The process of tissue healing
- The importance of asepsis and hygienic practices
- Wound creation, the principles of tissue handling and selection of a suitable surgical approach
- Possible causes of delayed or impaired wound healing or other post-surgical complications
- Preparation of personnel, animals, instruments and equipment for aseptic surgery
- The principles of Halstead and indicate how to achieve these
- The characteristics of different, commonly used instruments, suture materials and needles
- The importance of good technique in accessing surgical sites, handling tissues and repairing incisions
- The characteristics of different suture patterns and their applicability to different situations
- Describe common post-surgical complications and their causes
- The principles of post-surgical care and monitoring
- The planning of surgical procedures and discuss the competencies required of all personnel involved
- Particular aspects of care appropriate for animals before, during and after surgical or any other potentially painful intervention
The candidate must emonstrate competence in surgical techniques, including ablations, and incisions, how to place a suture correctly
Training in basic surgical principles can be provided by the clinical veterinarian or by a senior fellow with expertice from the research group, or by an external training provider.
The animal facility staff follow the outcome of surgery especially with regard to recovery from anesthesia, need for analgesia and wound as well as other complications.
Procedure specific training - Anestesia
Some basic theory include
- Define sedation, local and general anesthesia
- Define balanced anesthesia and indicate that this is best achieved
- Relate why and when sedation or anesthesia might be used for restraint.
- List the factors to be considered in pre-anesthetic evaluation of animals
- Choice of anesthetic agent.
- Discuss the relative merits / drawbacks and principles of selection of different agents in relevant species, including injectable and volatile agents
- Indicate the importance of minimizing stress prior to anesthesia
- Recognize when premedication is beneficial
- Describe and demonstrate the correct set-up, operation and maintenance of anesthetic equipment appropriate to the species concerned.
- Evaluate and appreciate the different levels and planes of anesthesia and list the factors indicating that an animal is suitably anaesthetized
- Describe methods of optimizing post anesthetic recovery
- Demonstrate an understanding of safe / good working practices with regard to use, storage and disposal of anesthetic and analgesic agents.
Practical training in anesthesia is offered in smaller groups
Continous education - update and maintenance of competence
Mattilsynet expect that people that work with reserach animals are continously retrained at least every 3-5 year and whenever it is neccesary to master new technology and procedures.