Home
Mitochondrial Medicine & Neurogenetics (MMN)

Scandomit 2010 - Programme

The programme for Scandomit 2010 is out. On January 20-22., 70 participants will meet in beautiful Solstrand Hotel to discussion various topics related to mitochondrial function, genetics and disease. Invited talks will be given by top researchers in the field.

Main content

Those who are not registered as participants but wish to attend the conference, are welcome. Please contact Professor Laurence Bindoff if you want to join on one or several of the days.

Updated programme 18.01.2010

 

Wednesday, 20 January


Session 1: Energy metabolism and bioenergetics

Chair - Karl Johan Tronstad

13.30-14.15

45min

David Nicholls

Studying mitochondrial bioenergetics in intact cells

14.15-14.30

15min

Hanne Hagland

Metabolic adaptations in tumour cells

14.30-14.45

15min

Julie Nikolaisen

Mitochondrial organisation in endothelial cells during angiogenesis

14.45-15.00

15min

Emilia Lohndal

A novel protein localisation assay based on subcellular NAD pools

15.00-15.15

15min

Andrey Nikiforov

The pathways of mitochondrial NAD generation from extracellular precursors

 

15.15-15.30

15min

Line Agledal

Expression of genes involved in NAD biosynthesis are altered by decreased subcellular NAD pools

15.30-16.00

30min

BREAK

 



Session 2: Mitochondrial DNA maintenance and replication

Chair - Hans Spelbrink

16.00-16.15

15min

Emil Ylikallio

Regulation of mtDNA copy number in vivo

16.15-16.30

15min

Atsushi Fukuoh

Depletion of mitochondrial DNA under RNAi of an mTERF family protein, DmTTF.

16.30-16.45

15min

Sjoerd Wanrooij

Mitochondrial RNA polymerase is needed for activation of the origin of light-strand DNA replication

16.45-17.00

15min

Wei Wang

Impaired mitochondrial DNA integrity alters differentiation outcomes of neural stem/progenitor cell in vitro

17.00-17.15

15min

Steffi Goffart

Twinkle and mtDNA replication

 


 


 


Setting up of posters



Thursday, 21 January


Session 3 Mitochondrial translation/physiology/models

Chair - Howy Jacobs

08.30-09.15

45min

Zosia Chrzanowska-Lightowlers

Exploiting Starvation: The STOP codon enigma

09.15-09.30

15min

Christopher Carroll

Physiological consequences of mitochondrial dysfunction

09.30-09.45

15min

Shanjun Chen

A cytoplasmic suppressor of tko25t

09.45-10.00

15min

Joni Nikkanen

Cis-regulatory elements of POLG1 expression with putative tissue-specificity

10.00-10.25

25min

Laurie Kaguni

A drosophila model of mitochondrial DNA transactions

10.25-10.45

20min

BREAK

 


 

Session 4 NAD-dependent regulation of mitochondrial function

Chair - Howy Jacobs

10.45-11.30

45min

Walter Rossmanith

Human mitochondrial (t)RNA processing: new enzyme, old job

11.30-11.45

15min

Lucia Valente

Sirtuins involvement in mitochondrial functions and mitochondrial DNA maintenance

11.45-12.00

15min

Christian Dölle

Identification of a novel target for mitochondrial mono-ADP- ribosylation

12.00-12.15

15min

Marc Niere

Is there poly ADP ribose metabolism in mitochondria?

12.15-12.30

15min

Alberto Sanz

Modulating Drosophila lifespan by the specific expression of alternatives enzymes in mitochondria.

12.30-13.30

 


LUNCH

 



Session 5 Mitochondrial Pathologies

Chair - Anu Wartiovaara

13.30-13.55

25 min

David Thorburn

Complex I deficiency: mouse models and the roles of new assembly factors

13.55-14.10

15min

Elsebet Østergaard

 

Mutations in a novel gene, C120ORF65, in two patients with a combined oxphos deficiency

14.10-14.25

15 min

Lisbeth Tranebjærg

 

OPA1 mutations and dual sensory impairment in two patients

14.25-14.40

15min

Petter Sanaker

 

Tissue splice differences and antisense splice corrections of ISCU myopathy

14.40-14.55

15min

Gittan Kollberg

Antisense oligonucleotide therapeutics for iron-sulphur cluster deficiency myopathy

14.55-15.15

20min

BREAK

 


15.15-15.35

20min

Julio Montoya

Three patients with new mtDNA mutations

15.35-15.50

15min

Tuula Lönnqvist

Dominantly inherited encephalitis mimicking mitochondrial disease

15.50-16.05

15min

Alexandra Götz

Severe CI and CIV deficiency with cardiac involvement in finnish infants

16.00-16.20

15min

Karin Hultin Jaderlund

A mitochondrially inherited neurological syndrome in dogs

16.20-18.00

 


 


POSTER SESSION

 

Friday, 22 January


Session 5 contd. Mitochondrial translation/models/haplotypes

Chair - Mathias Ziegler

09.00-09.45

45 min

Bob Lightowlers

New jobs for old terminators: the human mitochondrial translation termination family

09.45-10.00

15min

Kia Kemppainen

Expression of AOX rescues partial COX deficiency in Drosophila

10.00-10.15

15min

Eric Dufour

The alternative oxidase as a tool to compensate mitochondrial deficiencies; an update

10.15-10.30

15min

Matti Lakanmaa

TBA (NDI1)

10.30-11.00

20min

Erika Hagelberg

Mitochondrial DNA haplotypes in Norway

11.00-12.00

 


 


General Discussion/summary (Bindoff)

 

 

 

 

POSTERS

 

Name

Poster title

Ragna

Breines

Gadidae mitogenomics

Linn Nilsson

Hodneland

Mitochondrial biogenesis as a regulator in cell bioenergetics

Priit

Jõers

Mitochondrial DNA maintenance and topology in Drosophila melanogaster

Riikka

Jokinen

Tissue-Specific Control of Mitochondrial DNA Genetics

Esko

Kemppainen

tko Model of Mitochondrial Disorders

Tuomas

Komulainen

POLG1 R722H mutation associated with multiple mtDNA deletions and a neurological phenotype

Maja

Krzewinska

Mitochondrial DNA and Y chromosome variation in modern Norwegians

Saori

Morota

Human calcium induced mitochondrial permeability transition

Ilse

Paetau

Mouse model for infantile spinocerebellar ataxia

Nina

Rajala

Nucleoids in mtNDA maintenance

Marina

Toompuu

ELAC2 is involved in RNA19 processing

Tea

Tuomela

Creation of a mtDNA mutator in Drosophila melanogaster

Katrin

Viikov

Yeast mitochondrial DNA polymerase is highly processive, monomeric enzyme

Paulina

Wanrooij

Involvement of G-quadruplexes in pretermination of LSP-transcripts.

Eleonor

Åsander

Mitochondrial respiration in human platelets