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Brenk lab

Professor Ruth Brenk

The overall research goal of the Brenk lab is to improve methods used for structure-based drug design and to apply these methods to design inhibitors for enzymes with biological relevance. A key point in our research is the interplay of theoretical and experimental methods.

For more details, check out our research page.

Reseach funding from JPI-AMR
TPP riboswitch binding site

Exploration of the TPP riboswitch as a new target for antibiotics

Our EXPLORE network application aiming at targeting the TPP riboswitch for hit discovery for new antibiotics will receive funding from JPI-AMR! Other partners in the network are Daniel Lafontaine (Université de Sherbrooke, Canada), Matthias Mack (Mannheim University of Applied Sciences, Germany),...

New review article
TPP riboswitch binding site

Review about ligand design for riboswitches published

About state-of the art of riboswitch ligand design and future perspectives.

Webinar

Structure-based design of riboswitch and kinase ligands

A webinar about structure-based design of riboswitch and kinase ligands.

Research funding from NFR
Ribocil bound to FMN riboswitch

Chartering chemical space of riboswitch ligands - towards future antibiotics

The Brenk lab will receive funding from NFR for developing future antibiotics acting via riboswitch binding. This project will fund two postdoc positions for three years, one in the lab of Bengt Erik Haug (Department of Chemistry) and one in the Brenk group. We are looking forward to continuing an...

Researcher's grand prix
Illmar

Research to develop new antibiotics

Researcher's Grand Prix-cadidate Illimar Hugo Rekand is working to keep us healthy. He is investigating new opportunities for making new medicines in a world where antibiotic resistance is an increasing challenge.

We offer topics for the degree MSc in the area of structure-based drug design, e.g. molecular modelling, fragment screening and X-ray crystallography. Don't hestitate to contact us for chat to discuss what exactly we can offer and how we can tailor this to match your  interests.

The Brenk Lab is part of the Biorecognition Resarch Group.