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Professor Ruth Brenk

The overall research goal of the Brenk lab is to improve methods used for structure-based drug design and to apply these methods to design inhibitors for enzymes with biological relevance. A key point in our research is the interplay of theoretical and experimental methods.

For more details, check out our research page.

Review article
TOC graphic

Riboswitches as drug targets for antibiotics

Researchers at the Department of Biomedicine focus on large RNA structures in bacteria as a target for new antibiotics. Read the latest review article on riboswitches.

Preprint
A biochemical toolbox

Pushing structure-based design for new antibiotics

An Experimental Toolbox for Structure-Based Hit Discovery for P. Aeruginosa FabF, a Promising Target for Antibiotics

Price winner
Illimar Rekand

Price for oral presentation

Congratulations to Illimar who got the price for the second best oral presentation at the 34. Molecular Modeling Workshop 2020 in Erlangen. Well done!

Webinar

Exploring the TPP ribowitch as a new target for antibotics

Vipul has presented an update of our JPIAMR EXPLOR project on a recent JPIAMR workshop (25:55 to 38:02)

We offer topics for the degree MSc in the area of structure-based drug design, e.g. molecular modelling, fragment screening and X-ray crystallography. Don't hestitate to contact us for chat to discuss what exactly we can offer and how we can tailor this to match your  interests.

The Brenk Lab is part of the Biorecognition Research Group.