Mohn Cancer Research Laboratory

Malignant melanoma

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Malignant melanoma (cancer in melanocytes/nevi) is a type of cancer with particularly poor effect from conventional chemotherapy. However, in recent years, new immunotherapies have shown promising results and have become established as standard treatment.

We have two ongoing projects focusing on this disease: In one of the projects, we study the clonal evolution of metastases in melanoma patients with advanced disease and we evaluate the heterogeneity between different metastases within the same patients. In another project we analyze the underlying genetic causes of disease in families affected by a high number of melanoma cases, indicating an inherited factor to cause the risk of disease.  


Key publications: