Home

Brenk lab

Professor Ruth Brenk

The overall research goal of the Brenk lab is to improve methods used for structure-based drug design and to apply these methods to design inhibitors for enzymes with biological relevance. A key point in our research is the interplay of theoretical and experimental methods.

For more details, check out our research page.

Research news
TOC selectivity

New resarch article on selectivity

Our new paper on entangling selectivity determining features and on how to use this knowledge to design selective ligands has been published in J Med Chem!

NFR INFRA call poroposal rejected.
no new equipment

Full scores but no funding

The Nor-Openscreen application for this year's infrastructure call scored the highest possible marks in all categories! To quote from the reviewer comments: "This is an excellent proposal to enlarge and update existing infrastructure and services in chemical biology in Norway"....

Funding news
DLN

Towards better computational approaches and responsible innovation strategies in early drug discovery

Together with Nathalie Reuter and Bengt-Erik Haug from the Chemistry Department and Alexander Lundervold from the Høgskulen på Vestlandet (HVL) we got funding for the project «Towards better computational approaches and responsible innovation strategies in early drug discovery: application to...

Reseach funding from JPI-AMR
TPP riboswitch binding site

Exploration of the TPP riboswitch as a new target for antibiotics

Our EXPLORE network application aiming at targeting the TPP riboswitch for hit discovery for new antibiotics will receive funding from JPI-AMR! Other partners in the network are Daniel Lafontaine (Université de Sherbrooke, Canada), Matthias Mack (Mannheim University of Applied Sciences, Germany),...

Webinar

Structure-based design of riboswitch and kinase ligands

A webinar about structure-based design of riboswitch and kinase ligands.

We offer topics for the degree MSc in the area of structure-based drug design, e.g. molecular modelling, fragment screening and X-ray crystallography. Don't hestitate to contact us for chat to discuss what exactly we can offer and how we can tailor this to match your  interests.

The Brenk Lab is part of the Biorecognition Research Group.