Paraneoplastic Neurological Syndromes (PNS) research group

Paraneoplastic neurological syndromes (PNS) are autoimmune reactions that occur in connection with cancer.

Green fluorescent Purkinje cells in a cerebellar section

The picture is showing a 3D reconstruction of green fluorescent Purkinje neurons in a cerebellar section, imaged with a multiphoton microscope. Purkinje neurons are the main focus of our research since these neurons are affected in Paraneoplastic Cerebellar Degeneration (PCD).

Photo:

Meg Veruki and Manja Schubert

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The work of the group aims to find the mechanism behind the most common type of PNS, Paraneoplastic Cerebellar Degeneration (PCD), which is most often associated with small-cell lung cancer, ovarian cancer and breast cancer.

We hope to be able to identify the tumour at an earlier stage. Specific cancer treatment can then be started, and the chance for better recovery is increased.