Michael Sars Centre

News archive for Michael Sars Centre

Calcium signaling is important for many developmental processes but has been studied in only a handful of animal species throughout the entire span of embryonic development. A recent study sheds light on the importance of calcium waves during development in the tunicate Oikopleura dioica.
Chiara Castelletti and Vincenzo Perria are here in Bergen to reveal the secrets of Ciona’s development and its resilience to climate change.  
Blood systems allow the transport of nutrients throughout the body in many animals. A recent study looking at nutrient transport in a sea anemone highlights the simple cellular and molecular mechanisms that allowed animals to transport nutrients before the existence of complex circulatory systems.
Animals show a remarkable diversity of behaviors. How these behaviors are generated by the nervous system is an intensely studied topic in modern neurobiology. A new paper explores how the behavioral repertoire of chordates evolved into the breath-taking complexity often admired in vertebrates.
The paper from the Lynagh Group was highlighted as one of the journal’s Editors' Picks, which represent the top-rated papers published in JBC across the field of biological chemistry, and was selected for its ‘exceptional contribution to the field.’
Pawel Burkhardt is awarded with an ERC Consolidator Grant for his exciting project ORIGINEURO
Biological transitions: from molecules to evolution
The role of proteins affecting development via chromatin changes is poorly known outside bilaterian animals. Knocking out the Lsd1 gene in Nematostella shows its master role in the differentiation of cnidocytes, cells related to neurons that neutralize enemies by shooting a poisonous harpoon.
Comb jellies (ctenophores), one of the earliest-branching animal lineages, provide new insights into the evolutionary history of synapses and neurons. Ctenophores are fascinating marine organisms famous for locomotion by cilia and for their apparently simple nerve net. However, the molecular composition of ctenophore neurons was unknown, and it has been hypothesized that ctenophore neurons... Read more
An adaptable and user-friendly platform for 2D and 3D calcium imaging data analysis reveals the basic organization of neuronal dynamics in a simple chordate brain.
Choanoflagellates, protists closely related to animals, provide new insights into the evolutionary history of neurosecretory vesicles.
 Monday 15th and Tuesday 23rd March
Read more about Lionel Christiaen who will lead the Sars Centre from January 2021
Pioneer neurons provide new insights into the early nervous system development in annelids
Phylogenetic analysis sheds light on the evolutionary history of Polycomb mediated transcriptional repression in animals
After a long lasting lockdown following the Covid-19 outbreak, many of us are now back full time in the labs of the Sars Centre and we resume our experimental work with well refreshed ideas. This is possible due to the continuous care ensured by dedicated technical staff and a few scientists for our biological material, including our favorite marine organisms!
A new method by the Valen lab reveals modes and regulation of translation initiation
Gene expression profiling and CRISPR mutagenesis in Nematostella vectensis reveal the role of POU4 in the terminal differentiation of various neural cell types