Momentum delegate 2023

Anna-Simone Frank

Department of Informatics, Faculty of Mathematics and Natural Sciences

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I am a postdoctoral research fellow at the Computational Biology Unit (CBU), Department of Informatics. My B.Sc. and M.Sc. degrees in mathematics are from the Technical University of Munich, Germany, and I hold a PhD (2019) from the University of Oslo, Norway.

My current research focus is on developing mathematical models to explain dynamics of (i) macrophage polarization and (ii) ecological systems:

  • Macrophages are part of the innate immune response which can exhibit a wide range of different phenotypes. These phenotypes have different roles in disease outcomes. Polarization is the process in which phenotypes change and adapt. The mechanisms and condition underlying the phenotype switches as well as the probabilistic nature are not well understood. The aim is to increasing our understanding of the human immune response system.
  • For ecological marine systems, I aim to increase the understanding of why these systems transition between multiple stable states and the defining conditions. The metastable states define different productivity regimes of the system.