Centre for Cancer Biomarkers CCBIO
ccbio book release

New book from CCBIO

CCBIO with editors Lars A. Akslen and Randolph S. Watnick publishes a new book through Springer Publishing on August 31st. The title is Biomarkers of the Tumor Microenvironment - Basic Studies and Practical Applications. The book contains 22 chapters with more than 500 pages and multiple illustrations, with a general introduction to the topic (prologue) by Robert A. Weinberg. The foreword is written by Jean Paul Thiery. Several CCBIO investigators and affiliated professors have contributed.

the book cover.

Main content

This book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Practical applications, in terms of how biomarkers are increasingly included in therapy protocols, are also discussed. 

The book covers basic model studies of novel biomarkers and treatment targets of the microenvironment, exploration and validation of different classes of biomarkers in human tumors, and challenges of clinical implementation and treatment trials. It has high-quality illustrations and colour images of tissue-based biomarkers.

Biomarkers of the Tumour Microenvironment: Basic Studies and Practical Applications is aimed at research pathologists in the cancer field, and also cancer researchers from other backgrounds, especially those using morphology techniques and models focusing on cross-talk between different cell types in tumors.

"The importance of the microenvironment for tumor progress is a rapidly expanding and very exciting field", say Lars A. Akslen and Randolph S. Watnick, the book editors. "How immune cells, vascular cells, fibroblasts and the matrix co-operates and coordinate with tumor cells to advance cancer growth and spread is increasingly recognized. How companion biomarkers related to the tumor microenvironment can be used in diagnostic and therapeutic work is therefore a key question. We are very excited that this book project has been finally realized, and we would like to thank all contributors for their important work," Akslen and Watnick conclude.