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Shank3-SH3
An SH3 domain like no other at the post-synaptic density (27.06.2017)
The Shank family of proteins functions as a molecular scaffold in the neuronal post-synaptic density, enabling numerous protein-protein interactions. Shanks are large multi-domain molecules, and one of the conserved domains is an SH3 domain. Using high-resolution X-ray crystallography, we show that the SH3 domain in the Shank family has lost its canonical ligand-binding site.
Research
What is "necessary training" in health-related research ethics? (21.06.2017)
Associated Professor Kristine Bærøe spent one month as a visiting researcher at the Ethox Centre at Oxford University. She recently published a blog post on Ethoxblog, addressing the question of necessary training in research ethics.