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The Western Norway Regional Health Authorities (Helse Vest) has recently announced their project funding for 2025, and we are happy to see many Neuro-SysMed researchers in their announcement. In addition, other funding agencies have also granted support to our projects this fall.
CCBIO has a tradition of using the December meeting in its seminar series to add a different perspective and encourage our research environment to think outside of the box. This December, we had the pleasure of welcoming back Fran Balkwill, who has a unique experience in addition to her cancer research career.
The result of years of collaboration between CCBIO PI Jim Lorens and Rolf Brekken and other colleagues in the USA, Finland, Romania and Norway, is now published in Science Signaling, with research identifying nuclear AKT3 as a new biomarker of advanced malignancy and revealing the pathway that activates AKT3 to drive epithelial-to-mesenchymal transition in pancreatic cancer.
CCBIO recently held its signature course Methods in Cancer Biomarker Research (CCBIO905), September 25-27, 2024, at Haukeland University Hospital, providing the attending students with a full panel of standard and advanced methods with relevance for cancer biomarker research.
This year, one of CCBIO's students got the opportunity to have a 3-month research stay in Boston, due to CCBIO's INTPART collaboration with Harvard Medical School and Boston Children's Hospital. PhD Candidate Tessa Lohr reports of a great experience, highly recommending it to other young researchers.
Another PhD fellow completed her thesis at Center for Research on Cardiac Disease in Women. Lisa Grymyr received a PhD scholarship from Helse Vest. Her thesis was entitled: Left ventricular mechanics and oxygen demand in patients with severe obesity undergoing Roux-en-Y gastric bypass surgery
CNPase is an enzyme present at high levels in myelinating cells. Novel nanobody tools developed in an international collaboration were used to identify binding epitopes at atomic resolution and visualise myelin. Additionally, the nanobodies were used as intrabodies to bind to CNPase in living cells. These nanotools will be valuable for future research on myelin and its molecules.
Neuro-SysMed hosted its 2nd Annual Symposium on September 30 and October 1, 2024, at the historic Solstrand Hotel near Bergen, gathering 125 participants from various fields of neurological research. Among the distinguished guest speakers were EBV-MS Scientific Advisory Board Member Professor Gavin Giovannoni and EBV-MS Partner, Assistant Professor Kjetil Bjørnevik.
CCBIO's Co-Director Line Bjørge receives support for her group's project "Rethinking Ovarian Cancer: Developing Diagnostic and Functional Tools and Designing Innovative Multimodal Treatment Strategies."
This meeting at Solstrand August 28–31, 2024 was the 2nd Research Meeting in the INTPART collaboration between CCBIO and the Vascular Biology Program (VBP), Boston Children’s Hospital and Harvard Medical School, the first being the Iceland meeting in 2019. In 2019, 48 participants met in Iceland, and this year, 57 gathered at Solstrand.
Associate Professor Marc Vaudel and Professor Linda Gröning at the University of Bergen have each been awarded a prestigious ERC Consolidator Grant.
Oxygen is vital for human life and so is our ability to respond to low oxygen levels. Researchers at the University of Oxford and University of Bergen have uncovered new factors defining how human cells respond to hypoxia.
The Norwegian Cancer Society has recently allocated their 2024 grants to current cancer research projects. Eight researchers from Bergen made the final cut, including three from CCBIO.
An up-to-date description of the global burden of leukemia by subtype utilizing population-based cancer registries from around the world.
Kari Strøno Wagner-Larsen defended November 15, 2024 her doctoral work at the University of Bergen with the thesis "Advanced MRI for developing more personalized treatment strategies in uterine cervical cancer". Wagner-Larsen's doctoral work includes four studies showing that traditional as well as advanced, computer-assisted MRI analyses (radiomics) improve the risk assessment of patients with... Read more
Aromatic amino acid hydroxylases (AAAHs) like PAH, TH, and TPH are essential for producing key neurotransmitters and require iron and tetrahydrobiopterin to function. This study screened 307 histone deacetylase inhibitors and found that compounds like panobinostat can inhibit AAAHs at low micromolar concentrations, suggesting new therapeutic applications for these inhibitors.
A large study from Zambia, published in eClinicalMedicine, found that financial support combined with comprehensive sexuality education and community dialogue meetings, can moderately reduce adolescent births and increase the proportion of girls who complete basic education
PhD students Shanshan Xu and Robin Mzati Sinsamala from the Greenness, Air Pollution, and health (GAP) research group attended the Urban Transitions 2024 conference held from 5-7 November in Sitges, Spain, an event closely aligned with the GAP´s focus on the health impacts of urban air pollution and greenness exposure.

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