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Anni Vedeler's picture

Anni Vedeler

Professor
  • E-mailAnni.Vedeler@uib.no
  • Phone+47 55 58 64 35
  • Visitor Address
    Jonas Lies vei 91
  • Postal Address
    Postboks 7804
    5020 Bergen
Academic article
  • Show author(s) 2021. Annexin A2 binds the internal ribosomal entry site of c-myc mRNA and regulates its translation. RNA Biology. 1-19.
  • Show author(s) 2020. Structure of the ALS Mutation Target Annexin A11 Reveals a Stabilising N-Terminal Segment. Biomolecules. 1-17.
  • Show author(s) 2020. Co-localization of Interleukin-1α and Annexin A2 at the plasma membrane in response to oxidative stress. Cytokine.
  • Show author(s) 2019. Two tales of Annexin A2 knock-down: One of compensatory effects by antisense RNA and another of a highly active hairpin ribozyme. Biochemical Pharmacology. 253-263.
  • Show author(s) 2019. Cytotoxic saponins and other natural products from flowering tops of Narthecium ossifragum L. Phytochemistry. 67-77.
  • Show author(s) 2017. Post-translational modifications of Annexin A2 are linked to its association with perinuclear nonpolysomal mRNP complexes. FEBS Open Bio. 160-173.
  • Show author(s) 2017. Characterization of interactions between hepatitis C virus NS5B polymerase, annexin A2 and RNA - effects on NS5B catalysis and allosteric inhibition. Virology Journal. 1-11.
  • Show author(s) 2016. Toxic aromatic compounds from fruits of Narthecium ossifragum L. Phytochemistry. 76-85.
  • Show author(s) 2016. Reactive oxygen species exert opposite effects on Tyr23 phosphorylation of the nuclear and cortical pools of annexin A2. Journal of Cell Science. 314-328.
  • Show author(s) 2015. The native structure of annexin A2 peptides in hydrophilic environment determines their anti-angiogenic effects. Biochemical Pharmacology. 1-15.
  • Show author(s) 2015. Development of congenital stromal corneal dystrophy is dependent on export and extracellular deposition of truncated decorin. Investigative Ophthalmology and Visual Science. 2909-2915.
  • Show author(s) 2014. Two-stage translational control of dentate gyrus LTP consolidation is mediated by sustained BDNF-TrkB signaling to MNK. Cell reports. 1430-1445.
  • Show author(s) 2014. Effect of serine phosphorylation and ser25 phospho-mimicking mutations on nuclear localisation and ligand interactions of annexin A2. Journal of Molecular Biology (JMB). 2486-2499.
  • Show author(s) 2013. Influenza A virus protein PB1-F2 from different strains shows distinct structural signatures. Biochimica et Biophysica Acta - Proteins and Proteomics. 568-582.
  • Show author(s) 2013. Domains I and IV of annexin A2 affect the formation and integrity of in vitro capillary-like networks. PLOS ONE. 12 pages.
  • Show author(s) 2007. The mRNA-binding site of annexin A2 resides in helices C-D of its domain IV. Journal of Molecular Biology (JMB). 1367-1378.
  • Show author(s) 2006. Engineering, biophysical characterisation and binding properties of a soluble mutant form of annexin A2 domain IV that adopts a partially folded conformation. Journal of Molecular Biology (JMB). 469-481.
  • Show author(s) 2006. Annexin A2 recognises a specific region in the 3 '-UTR of its cognate messenger RNA. BBA - Molecular Cell Research. 1325-1334.
  • Show author(s) 2005. Ubiquitinated annexin A2 is enriched in the cytoskeleton fraction. FEBS Letters. 203-206.
  • Show author(s) 2005. Annexin A2 binds to the localization signal in the 3 ' untranslated region of c-myc mRNA. The FEBS Journal. 413-421.
  • Show author(s) 2000. Annexin II is associated with mRNAs which may constitute a distinct subpopulation. Biochemical Journal. 565-572.
  • Show author(s) 1998. Ribosomal proteins sustain morphology, function and phenotype in acute myeloid leukemia blasts. Leukemia Research. 329-339.
  • Show author(s) 1998. Ribosomal proteins sustain morphology, function and phenotype in acute myeloid leukemia blasts. Leukemia Research. 329-339.
  • Show author(s) 1995. The sequestration of mRNA in the cytoskeleton and other subcellular structures. Advances in Molecular and Cell Biology. 41-74.
  • Show author(s) 1995. Changes in the distribution of actin mRNA in different polysome fractions following stimulation of MPC-11 cells. Molecular and Cellular Biochemistry. 107-115.
  • Show author(s) 1994. Free, cytoskeletal-bound and mambrane-bound polysomes isolated from MPC-11 cells differ in their complement of poly(A) binding proteins. Molecular and Cellular Biochemistry. 131-139.
  • Show author(s) 1994. Changes in distribution of actin mRNA in different polysome fractions following stimulation of MPC-11 cells. Molecular and Cellular Biochemistry. 107-115.
  • Show author(s) 1993. The involvement of microfilaments in protein synthesis; effects of insulin. International journal of biochemistry. 853-864.
  • Show author(s) 1993. The effect of insulin on proteins associated with free, cytoskeletal-bound and membranes-bound polysome populations. Cell Biology International. 1065-1073.
  • Show author(s) 1992. The effects of insulin, cycloheximide and phalloidin on the content of actin and p35 in extracts prepared from the nuclear fraction of Krebs II ascites cells. Molecular and Cellular Biochemistry. 187-194.
  • Show author(s) 1992. Morphological changes in Krebs II ascites tumour cells induced by insulin are associated with differences in protein composition and altered amounts of free, cytoskeletal-bound and membrane-bound polysomes. Molecular and Cellular Biochemistry. 131-140.
  • Show author(s) 1992. Insulin. Signal transmission and short term effects on the cytoskeleton and protein synthesis. International journal of biochemistry. 183-191.
  • Show author(s) 1991. The isolation of three distinct populations of polysomes from eukaryotic cells. Biochemical Society Transactions. 1108-1111.
  • Show author(s) 1991. The characterization of free, cytoskeletal- and membrane-bound polysomes in Krebs 2 ascites and 3T3 cells. Molecular and Cellular Biochemistry. 183-193.
  • Show author(s) 1991. Insulin induces changes in the subcellular distribution of actin and 5'-nucleotidase. Molecular and Cellular Biochemistry. 67-74.
  • Show author(s) 1991. Differences in the content of acitin-binding proteins in subcellular fractions prepared from Krebs 2 ascites cells. Biochemical Society Transactions. 1140-1141.
  • Show author(s) 1991. Differences in patterns of proteins isolated from polysomes in free, cytoskeletal-bound and membrane-bound fractions in MPC-11 cells incubated with insulin. Biochemical Society Transactions. 1138-1139.
  • Show author(s) 1991. Changes in amounts of polysomes in free, cytoskeletal-bound and membrane-bound populations in Krebs 2 ascites cells subjected to different growth conditions. Biochemical Society Transactions. 1136-1137.
Lecture
  • Show author(s) 2013. PB1-F2 –Structural signatures of highly pathogenic influenza viruses.
Academic lecture
  • Show author(s) 2018. Nytt potensielt virkestoff fra urgammel iransk medisinplante.
  • Show author(s) 2017. The association of Annexin A2 with polysomes and translationally inactive mRNP complexes is regulated by post-translational modifications.
  • Show author(s) 2017. Rome –en unik kilde til nye antileukemi naturprodukter.
Short communication
  • Show author(s) 2016. Extracellular vesicles released from cells exposed to reactive oxygen species increase annexin A2 expression and survival of target cells exposed to the same conditions. Communicative & Integrative Biology.
Masters thesis
  • Show author(s) 2017. Effekt av utvalgte unike naturstoffer på celleviabilitet og sårtilheling i nevroendokrine PC12 celler med særlig fokus på Annexin A2.
  • Show author(s) 2016. Annexin A7 and Annexin A11 as mRNA-binding Proteins.
  • Show author(s) 2015. The RNA-Binding Abilities of the Rat Annexins.
  • Show author(s) 2014. The Effect of miR-155 on the Expression of Annexin A2.
  • Show author(s) 2014. Effekt av hypoksia på Annexin A2 i mitokondrier fra HepG2- og PC12-celler.
  • Show author(s) 2013. The Localization and Binding to mRNA of Wild Type Annexin A2 and Its Tyrosine-23 Mutants.
  • Show author(s) 2013. Annexin A1, Annexin A2 and Annexin A4, but not Annexin A5 and Annexin A10, Are Able to Bind RNA.
  • Show author(s) 2012. The Response to As3+ and As5+ in Schizosaccharomyces pombe - Function of Ibp1.
  • Show author(s) 2011. Mutations of Serine 25 of Annexin A2 and their Effects on Structure and Function.
  • Show author(s) 2011. Annexin A2 Tyr-­23 Phosphorylation and Its Effect on Ubiquitination and Sumoylation.
  • Show author(s) 2010. The Effect of Annexin A2 Peptides in Angiogenesis In Vitro.
  • Show author(s) 2010. DETERMINATION OF THE CONFORMATIONS ADOPTED BY CXCR4 AND CCR5 AT THE CELL SURFACE.
  • Show author(s) 2009. Annexin A2 is sumoylated in vitro and in vivo.
  • Show author(s) 2008. THE ROLE OF ANNEXIN A2 IN ANGIOGENESIS.
  • Show author(s) 2006. The Effect of the Binding of Annexin A2 to the Untranslated Regions of c-myc mRNA on the in vitro Translation of Reporter Protein.
Doctoral dissertation
  • Show author(s) 2015. Phosphorylation of Annexin A2. Regulation of subcellular localisation and function.
  • Show author(s) 1990. The isolation of free, cytoskeletal-bound and membrane-bound polysomes : the effects of insulin on polysome and actin distribution in eukaryotic cells.
Poster
  • Show author(s) 2007. The Effect of the Binding of Annexin A2 to the Untranslated Regions of c-myc mRNA on the in vitro Translation of Reporter Protein.
  • Show author(s) 2006. Engineering of mRNA chimeras to study the role of Annexin A2 in c-myc mRNA translation.
  • Show author(s) 2003. Ubiquitin conjugates of annexin 2 are enriched in cytoskeleton-associated messenger ribonucleoprotein complexes.
Academic literature review
  • Show author(s) 2017. Protein phosphorylation and its role in the regulation of Annexin A2 function. Biochimica et Biophysica Acta - General Subjects. 2515-2529.
  • Show author(s) 2013. Arrivals and departures at the plasma membrane: direct and indirect transport routes. Cell and Tissue Research. 5-20.
  • Show author(s) 2012. Multiple roles of annexin A2 in post-transcriptional regulation of gene expression. Current Protein & Peptide Science. 401-412.

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