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Anni Vedeler's picture

Anni Vedeler

Professor
  • E-mailAnni.Vedeler@uib.no
  • Phone+47 55 58 64 35
  • Visitor Address
    Jonas Lies vei 91
  • Postal Address
    Postboks 7804
    5020 Bergen
Academic article
  • 2019. Two tales of Annexin A2 knock-down: One of compensatory effects by antisense RNA and another of a highly active hairpin ribozyme. Biochemical Pharmacology. 253-263.
  • 2019. Cytotoxic saponins and other natural products from flowering tops of Narthecium ossifragum L. Phytochemistry. 67-77.
  • 2017. Post-translational modifications of Annexin A2 are linked to its association with perinuclear nonpolysomal mRNP complexes. FEBS Open Bio. 160-173.
  • 2017. Characterization of interactions between hepatitis C virus NS5B polymerase, annexin A2 and RNA - effects on NS5B catalysis and allosteric inhibition. Virology Journal. 1-11.
  • 2016. Toxic aromatic compounds from fruits of Narthecium ossifragum L. Phytochemistry. 76-85.
  • 2016. Reactive oxygen species exert opposite effects on Tyr23 phosphorylation of the nuclear and cortical pools of annexin A2. Journal of Cell Science. 314-328.
  • 2015. The native structure of annexin A2 peptides in hydrophilic environment determines their anti-angiogenic effects. Biochemical Pharmacology. 1-15.
  • 2015. Development of congenital stromal corneal dystrophy is dependent on export and extracellular deposition of truncated decorin. Investigative Ophthalmology and Visual Science. 2909-2915.
  • 2014. Two-stage translational control of dentate gyrus LTP consolidation is mediated by sustained BDNF-TrkB signaling to MNK. Cell reports. 1430-1445.
  • 2014. Effect of serine phosphorylation and ser25 phospho-mimicking mutations on nuclear localisation and ligand interactions of annexin A2. Journal of Molecular Biology. 2486-2499.
  • 2013. Influenza A virus protein PB1-F2 from different strains shows distinct structural signatures. Biochimica et Biophysica Acta - Proteins and Proteomics. 568-582.
  • 2013. Domains I and IV of annexin A2 affect the formation and integrity of in vitro capillary-like networks. PLOS ONE. 12 pages.
  • 2007. The mRNA-binding site of annexin A2 resides in helices C-D of its domain IV. Journal of Molecular Biology. 1367-1378.
  • 2006. Engineering, biophysical characterisation and binding properties of a soluble mutant form of annexin A2 domain IV that adopts a partially folded conformation. Journal of Molecular Biology. 469-481.
  • 2006. Annexin A2 recognises a specific region in the 3 '-UTR of its cognate messenger RNA. BBA - Molecular Cell Research. 1325-1334.
  • 2005. Ubiquitinated annexin A2 is enriched in the cytoskeleton fraction. FEBS Letters. 203-206.
  • 2005. Annexin A2 binds to the localization signal in the 3 ' untranslated region of c-myc mRNA. The FEBS Journal. 413-421.
  • 2000. Annexin II is associated with mRNAs which may constitute a distinct subpopulation. Biochemical Journal. 565-572.
  • 1998. Ribosomal proteins sustain morphology, function and phenotype in acute myeloid leukemia blasts. Leukemia Research. 329-339.
  • 1998. Ribosomal proteins sustain morphology, function and phenotype in acute myeloid leukemia blasts. Leukemia Research. 329-339.
  • 1995. The sequestration of mRNA in the cytoskeleton and other subcellular structures. Advances in Molecular and Cell Biology. 41-74.
  • 1995. Changes in the distribution of actin mRNA in different polysome fractions following stimulation of MPC-11 cells. Molecular and Cellular Biochemistry. 107-115.
  • 1994. Free, cytoskeletal-bound and mambrane-bound polysomes isolated from MPC-11 cells differ in their complement of poly(A) binding proteins. Molecular and Cellular Biochemistry. 131-139.
  • 1994. Changes in distribution of actin mRNA in different polysome fractions following stimulation of MPC-11 cells. Molecular and Cellular Biochemistry. 107-115.
  • 1993. The involvement of microfilaments in protein synthesis; effects of insulin. International journal of biochemistry. 853-864.
  • 1993. The effect of insulin on proteins associated with free, cytoskeletal-bound and membranes-bound polysome populations. Cell Biology International. 1065-1073.
  • 1992. The effects of insulin, cycloheximide and phalloidin on the content of actin and p35 in extracts prepared from the nuclear fraction of Krebs II ascites cells. Molecular and Cellular Biochemistry. 187-194.
  • 1992. Morphological changes in Krebs II ascites tumour cells induced by insulin are associated with differences in protein composition and altered amounts of free, cytoskeletal-bound and membrane-bound polysomes. Molecular and Cellular Biochemistry. 131-140.
  • 1992. Insulin. Signal transmission and short term effects on the cytoskeleton and protein synthesis. International journal of biochemistry. 183-191.
  • 1991. The isolation of three distinct populations of polysomes from eukaryotic cells. Biochemical Society Transactions. 1108-1111.
  • 1991. The characterization of free, cytoskeletal- and membrane-bound polysomes in Krebs 2 ascites and 3T3 cells. Molecular and Cellular Biochemistry. 183-193.
  • 1991. Insulin induces changes in the subcellular distribution of actin and 5'-nucleotidase. Molecular and Cellular Biochemistry. 67-74.
  • 1991. Differences in the content of acitin-binding proteins in subcellular fractions prepared from Krebs 2 ascites cells. Biochemical Society Transactions. 1140-1141.
  • 1991. Differences in patterns of proteins isolated from polysomes in free, cytoskeletal-bound and membrane-bound fractions in MPC-11 cells incubated with insulin. Biochemical Society Transactions. 1138-1139.
  • 1991. Changes in amounts of polysomes in free, cytoskeletal-bound and membrane-bound populations in Krebs 2 ascites cells subjected to different growth conditions. Biochemical Society Transactions. 1136-1137.
Lecture
  • 2013. PB1-F2 –Structural signatures of highly pathogenic influenza viruses.
Academic lecture
  • 2018. Nytt potensielt virkestoff fra urgammel iransk medisinplante.
  • 2017. The association of Annexin A2 with polysomes and translationally inactive mRNP complexes is regulated by post-translational modifications.
  • 2017. Rome –en unik kilde til nye antileukemi naturprodukter.
Short communication
  • 2016. Extracellular vesicles released from cells exposed to reactive oxygen species increase annexin A2 expression and survival of target cells exposed to the same conditions. Communicative & Integrative Biology.
Masters thesis
  • 2017. Effekt av utvalgte unike naturstoffer på celleviabilitet og sårtilheling i nevroendokrine PC12 celler med særlig fokus på Annexin A2.
  • 2016. Annexin A7 and Annexin A11 as mRNA-binding Proteins.
  • 2015. The RNA-Binding Abilities of the Rat Annexins.
  • 2014. The Effect of miR-155 on the Expression of Annexin A2.
  • 2014. Effekt av hypoksia på Annexin A2 i mitokondrier fra HepG2- og PC12-celler.
  • 2013. The Localization and Binding to mRNA of Wild Type Annexin A2 and Its Tyrosine-23 Mutants.
  • 2013. Annexin A1, Annexin A2 and Annexin A4, but not Annexin A5 and Annexin A10, Are Able to Bind RNA.
  • 2012. The Response to As3+ and As5+ in Schizosaccharomyces pombe - Function of Ibp1.
  • 2011. Mutations of Serine 25 of Annexin A2 and their Effects on Structure and Function.
  • 2011. Annexin A2 Tyr-­23 Phosphorylation and Its Effect on Ubiquitination and Sumoylation.
  • 2010. The Effect of Annexin A2 Peptides in Angiogenesis In Vitro.
  • 2010. DETERMINATION OF THE CONFORMATIONS ADOPTED BY CXCR4 AND CCR5 AT THE CELL SURFACE.
  • 2009. Annexin A2 is sumoylated in vitro and in vivo.
  • 2008. THE ROLE OF ANNEXIN A2 IN ANGIOGENESIS.
  • 2006. The Effect of the Binding of Annexin A2 to the Untranslated Regions of c-myc mRNA on the in vitro Translation of Reporter Protein.
Doctoral dissertation
  • 2015. Phosphorylation of Annexin A2. Regulation of subcellular localisation and function.
  • 1990. The isolation of free, cytoskeletal-bound and membrane-bound polysomes : the effects of insulin on polysome and actin distribution in eukaryotic cells.
Poster
  • 2007. The Effect of the Binding of Annexin A2 to the Untranslated Regions of c-myc mRNA on the in vitro Translation of Reporter Protein.
  • 2006. Engineering of mRNA chimeras to study the role of Annexin A2 in c-myc mRNA translation.
  • 2003. Ubiquitin conjugates of annexin 2 are enriched in cytoskeleton-associated messenger ribonucleoprotein complexes.
Academic literature review
  • 2017. Protein phosphorylation and its role in the regulation of Annexin A2 function. 2515-2529.
  • 2013. Arrivals and departures at the plasma membrane: direct and indirect transport routes. 5-20.
  • 2012. Multiple roles of annexin A2 in post-transcriptional regulation of gene expression. 401-412.

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