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George William Francis

Professor
  • E-mailGeorge.Francis@uib.no
  • Phone+47 55 58 34 65
  • Visitor Address
    Realfagbygget, Allégt. 41
    Room 
    3040
  • Postal Address
    Postboks 7803
    5020 BERGEN

Natural product chemistry. Analysis and identification of organic compounds from plants and microorganisms. Compound types studied: alkaloids, anthraquinones, carotenoids, terpenoids in general.

Mass spectrometry: DART in analysis.

Kjem 233 Mass Spectrometry

Kjem 238 Pharmacognosy

Academic article
  • 2017. Non-Polar Natural Products from Bromelia laciniosa, Neoglaziovia variegata and Encholirium spectabile (Bromeliaceae). Molecules.
  • 2015. Changes in the composition of aromatherapeutic citrus oils during evaporation. Evidence-based Complementary and Alternative Medicine (eCAM). 6 pages.
  • 2014. Preliminary photochemical studies of fluorene in various aqueous media. American Journal of Scientific and Industrial Research. 97-103.
  • 2014. Differential evaporation of aromatherapy mint oils. Air quality, atmosphere and health. 481-487.
  • 2013. Novel GHB-derived natural products from European mistletoe (Viscum album). Pharmaceutical Biology. 981-986.
  • 2012. The use of lightweight expanded clay aggregate (LECA) as sorbent for PAHs removal from water. Journal of Hazardous Materials. 360-365.
  • 2012. Pyrolytic formation of pyrolytic aromatic hydrocarbons from sesquiterpenes. Food Chemistry. 1316-1322.
  • 2012. Novel aminoalkaloids from European mistletoe (Viscum album L.). Phytochemistry Letters. 677-681.
  • 2011. Pyrolytic formation of polyaromatic hydrocarbons from steroid hormones. Food Chemistry. 1466-1472.
  • 2008. Comparison of high-pressure liquid chromatography (HPLC) and Griess reagent-spectroscopic methods for the measurement of nitrate in serum from healthy individuals in the Nordic countries. Clinical Biochemistry. 1474-1481.
  • 2004. Volatile compounds in crude Salvadora persica extracts. Pharmaceutical Biology. 399-404.
  • 2004. Khat (Catha edulis)-induced apoptosis is inhibited by antagonists of caspase-1 and -8 in human leukaemia cells. British Journal of Cancer. 1726-1726.
  • 2003. Volatile compounds in crude Salvadora Persica extracts. Pharmaceutical Biology. 399-404.
  • 2002. In vitro microbial effects of crude miswak extracts on oral pathogens. Saudi Dental Journal. 26-32.
  • 2002. In vitro Antimicrobial Effects of Crude Miswak Extracts on Oral Pathogens. Saudi Dental Journal. 26-32.
  • 2001. Vihrean kemian opetus tahtaimessa(Green Chemistry Teaching in View). Kemia-Kemi. 748-750.
  • 2001. Simple syntheses of N-alkylated spermidine fragments and analogues of the spermine alkaloid kukoamine A. Tetrahedron Letters. 1579-1582.
  • 1998. Preparation and Properties of Enantiomerically Pure N-tritylamino acid fluorides. Acta Chemica Scandinavica. 1144-1150.
  • 1998. Aminolysis of N-Tritylamino Acis Benzyltriaz Esters with Concentrated Aqueous amines and applications in synthesis. Acta Chemica Scandinavica. 227-231.
  • 1998. 1H and 13C NMR Studies of Anthraquinone glycosides from Rhamnus frangula. Magnetic Resonance in Chemistry. 769-772.
  • 1998. (S),(E)-5-Methoxycarbonyl-3-triphenylmethylaminohex-4-en-olide. Acta Crystallographica Section C: Crystal Structure Communications. 267-269.
  • 1998. (S),(E)-5-Methoxycarbonyl-3-triphenylmethylaminohex- 4-en-4-olide. Acta Crystallographica Section C: Crystal Structure Communications. 267-269.
  • 1996. NMR studies of TRH and Analogues Incorporating D-Hisidine and 4-Hydroxyl-L-Proline. Acta Chemica Scandinavica. 411-416.
  • 1996. %1H and %13C NMR studies of some athraquinones and anthracenetetrones. Magnetic Resonance in Chemistry. 1043-1047.
  • 1994. Synthesis of a new kainic acid based selective ligand as a potential photoaffinity label of non-NMDA excitatory amino acid receptors in chicken brain. Acta Chemica Scandinavica. 76-79.
  • 1994. Redox N-Alkylation of tosyl protected amino acid and peptide esters. Dionissios papaioannou, constantinos athanassopoulos. Acta Chemica Scandinavica. 324-333.
  • 1994. Redox N-Alkylation of Tosyl Protected Amino Acid and Peptide Esters. Acta Chemica Scandinavica. 324-333.
  • 1994. Ampelopsin 7-glucoside and other dihydroflavonol 7-glucosides form needles of picea abies. Phytochemistry. 550-552.
  • 1994. Ampelopsin 7-0-_b-glucoside and other dihydroflavonol 7-glucosides from needles of Norway spruce, picea abies. Phytochemistry. 550.
  • 1993. Myricetin 3,4'-Diglucoside and Kampherol Derivatives from Needles of Norway Spruce, Picea Abies. Phytochemistry. 179-181.
  • 1993. Assignments of the %1H and %13C NMR Spectra of trans-4-hydroxy-N-9-fluorenylmethoxycarbonyl-L-proline Using One- and Two-Dimensional NMR Spectroscopy. Magnetic Resonance in Chemistry. 876-877.
  • 1993. An Improved HPLC System for the Analysis of Photosynthetic Pigments. Chromatographia. 189.
  • 1992. NMR-study of some anthraquinones in rhubarb. Magnetic Resonance in Chemistry. 359-360.
  • 1992. Myricetin 3,4'-diglucoside and Kaempferol Derivatives from Needles of Norwegian Spruce, Picea Abies. Phytochemistry.
  • 1992. An improved HPLC System for the Analysis of Photosynthetic Pigments. Chromatographia.
  • 1991. Solid-Phase Synthesis and Spectroscopic Studies of TRH Analogues Incorporating Cis- and trans-4-Hydroxy-L-Proline. Acta Chemica Scandinavica. 1047-1054.
Popular scientific lecture
  • 2000. Tematisk nettverk i kjemi.
  • 2000. Nomenklatur i organisk kjemi.
  • 2000. Internasjonalisering - I vesten eller i verden.
  • 2000. Faglige arbeid over landegrensen.
  • 1997. @<Tittel ikke oppgitt@>.
  • 1997. @<Tittel ikke oppgitt@>.
Academic lecture
  • 2005. Molecular mechanisms of apoptosis induced by khat extract and its alkaloids cathinone and cathine in acute myeloid leukemia.
  • 2005. Mechanisms of apoptosis induction by khat alkaloids in leukaemia cells.
  • 2001. Preliminary Report of ECTN Working Group on Green and Sustainable Chemistry in European Universities.
  • 2000. The Principles of ECTS.
  • 2000. Erfaringer med ECTS.
  • 2000. An Introduction to ECTS.
  • 1999. Videreføring av ECTS.
  • 1999. Introduksjon til ECTS.
  • 1999. ECTS. Hva er det?
  • 1999. ECTS systemet, erfaring og praksis.
  • 1999. Chromatographic Fractionation of Petroleum.
  • 1998. Introduction til det europeiske kredit-overførings systemet (ECTS).
  • 1998. ECTS of erfaringer med systemet i Norge.
  • 1997. European Credit Transfer Systems (ECTS).
  • 1997. Core chemistry (organic and physical chemistry) in Norway.
Reader opinion piece
  • 2009. Reply to: On the importance of the use of proper approaches for comparison of analytical methods for serum nitrate and evaluation of reference concentrations. By Dr. Dimitrios Tsikas and Dr. Jens M Hohlfeld. Clinical Biochemistry. 1197-1199.
Thesis at a second degree level
  • 2005. Analyse av prdukter fra fire seskviterpener ved hjelp av GC-MC.
Masters thesis
  • 2011. Analyse av psykofarmaka-Metodeutvikling for kromatografisk analyse av utvalgte antidepressiva og antipsykotika i serum.
Academic chapter/article/Conference paper
  • 2006. The Use of PLC for Separation of Natural Pigments. 22 pages.
  • 2004. Techniques of pigment identification. 49 pages.
Encyclopedia article
  • 2003. Natural pigments. 697-732. In:
    • 2003. Handbook of Thin-Layer Chromatography. 89.
  • 2000. Pigments: Thin-Layer(Okabar) Chromatography Encyclopedia of Separation Science. 3839-3850. In:
    • 2000. Encyclopedia of Separation Science.
Abstract
  • 2005. The role of Bcl-2 in apoptosis induced by khat (Catha edulis) in acute myeloid leukemia cell lines. Blood. 195b-195b.
Poster
  • 2017. Non-polar natural products from the drought resistant Brazilian medicinal plants Bromelia laciniosa, Neoglaziovia variegata and Encholirium spectabile (Bromeliaceae).
  • 2001. Analysis of Pyrolysis Products of Sex Hormones by GC-MS.

More information in national current research information system (CRIStin)

BSc (Glasgow), MSc (Glasgow), Dr.ing. (Trondheim), Fil.dr. (Stockholm.

Investigation of mistletoe

Aromatherapy