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  • E-mailJohan.Ferno@uib.no
  • Visitor Address
    Haukeland universitetssykehus, Laboratoriebygget
  • Postal Address
    Postboks 7804
    5020 Bergen
Journal articles
  • Al-Massadi, Omar; Fernø, Johan; Dieguez, Carlos; Nogueiras, Rubén; Quiñones, Mar. 2019. Glucagon control on food intake and energy balance. International Journal of Molecular Sciences. 20:3905: 1-12. doi: 10.3390/ijms20163905
  • Fernø, Johan; Strand, Kristina; Mellgren, Gunnar; Stiglund, Natalie; Björkström, Niklas K. 2019. Natural killer cells as sensors of adipose tissue stress. Trends in endocrinology and metabolism. 1-10. doi: 10.1016/j.tem.2019.08.011
  • Gudbrandsen, Oddrun Anita; Dankel, Simon N; Skumsnes, Lillian; Flølo, Tone Nygaard; Folkestad, Oddry H; Nielsen, Hans Jørgen; Våge, Villy; Mohn, Arne-Christian; Nedrebø, Bjørn Gunnar; Sagen, Jørn V.; Fernø, Johan; Mellgren, Gunnar. 2019. Short-term effects of Vertical sleeve gastrectomy and Roux-en-Y gastric bypass on glucose homeostasis. Scientific Reports. 9:14817: 1-7. doi: 10.1038/s41598-019-51347-x
  • Quiñones, Mar; Fernø, Johan; Dieguez, Carlos; Nogueiras, Rubén; Al-Massadi, Omar. 2019. Exciting advances in GPCR-based drugs discovery for treating metabolic disease and future perspectives. Expert Opinion on Drug Discovery. 14: 421-431. doi: 10.1080/17460441.2019.1583642
  • Stiglund, Natalie; Strand, Kristina; Cornillet, Martin; Stål, Per; Thorell, Anders; Zimmer, Christine L.; Näslund, Erik; Karlgren, Silja; Nilsson, Henrik; Mellgren, Gunnar; Fernø, Johan; Hagström, Hannes; Björkström, Niklas K. 2019. Retained NK cell phenotype and functionality in non-alcoholic fatty liver disease. Frontiers in Immunology. 10:1255: 1-13. doi: 10.3389/fimmu.2019.01255
  • Svärd, Jessica; Røst, Therese Halvorsen; Sommervoll, Camilla Elise Nergård; Haugen, Christine; Gudbrandsen, Oddrun Anita; Christensen, Anne Elisabeth; Rødahl, Eyvind; Fernø, Johan; Dankel, Simon N; Sagen, Jørn V.; Mellgren, Gunnar. 2019. Absence of the proteoglycan decorin reduces glucose tolerance in overfed male mice. Scientific Reports. 9. doi: 10.1038/s41598-018-37501-x
  • Barja-Fernandez, Silvia; Moreno-Navarrete, Jose Maria; Folgueira, Cintia; Xifra, Gemma; Sabater, Monica; Castelao, Cecilia; Fernø, Johan; Leis, Rosaura; Diéguez, Carlos; Casanueva, Felipe F; Ricart, Wifredo; Seoane, Luisa M.; Fernández-Real, José Manuel; Nogueiras, Rubén. 2018. Plasma ANGPTL-4 is Associated with Obesity and Glucose Tolerance: Cross-Sectional and Longitudinal Findings. Molecular Nutrition & Food Research. 62. doi: 10.1002/mnfr.201800060
  • Gonzalez-Garcia, Ismael; Contreras, Cristina; Estévez-Salguero, Ánxela; Ruiz-Pino, Francisco; Colsh, Benoit; Pensado, Ivan; Liñares-Pose, Laura; Rial-Pensado, Eva; Martínez De Morentin, Pablo Blanco; Fernø, Johan; Dieguez, Carlos; Nogueiras, Ruben; Le Stunff, Herve; Magnan, Christophe; Tena-Sempere, Manuel; Lopez, Miguel. 2018. Estradiol Regulates Energy Balance by Ameliorating Hypothalamic Ceramide-Induced ER Stress. Cell reports. 25: 413-423.e5. doi: 10.1016/j.celrep.2018.09.038
  • González-García, Ismael; de Morentin, Pablo B. Martínez; Estévez-Salguero, Ánxela; Contreras, Cristina; Romero-Picó, Amparo; Fernø, Johan; Nogueiras, Rubén; Diéguez, Carlos; Tena-Sempere, Manuel; Tovar, Sulay; López, Miguel. 2018. mTOR signaling in the arcuate nucleus of the hypothalamus mediates the anorectic action of estradiol. Journal of Endocrinology. 238: 177-186. doi: 10.1530/JOE-18-0190
  • Porteiro, Begoña; Fondevila, Marcos F.; Buque, Xabier; Gonzalez-Rellan, Maria J.; Fernandez, Uxia; Mora, Alfonso; Beiroa, Daniel; Senra, Ana; Gallego, Rosalía; Fernø, Johan; López, Miguel; Sabio, Guadalupe; Diéguez, Carlos; Aspichueta, Patricia; Nogueiras, Rubén. 2018. Pharmacological stimulation of p53 with low-dose doxorubicin ameliorates diet-induced nonalcoholic steatosis and steatohepatitis. Molecular Metabolism. 8: 132-143. doi: 10.1016/j.molmet.2017.12.005
  • Quiñones, Mar; Al-Massadi, Omar; Folgueira, Cintia; Bremser, Stephan; Gallego, Rosalia; Torres-Leal, Leonardo; Haddad-Tóvolli, Roberta; García-Caceres, Cristina; Hernandez-Bautista, Rene; Lam, Brian Y.H.; Beiroa, Daniel; Sanchez-Rebordelo, Estrella; Senra, Ana; Malagon, José A.; Valerio, Patricia; Fondevila, Marcos F.; Fernø, Johan; Malagon, Maria M.; Contreras, Raian; Pfluger, Paul; Brüning, Jens C.; Yeo, Giles; Tschöp, Matthias; Diéguez, Carlos; López, Miguel; Claret, Marc; Kloppenburg, Peter; Sabio, Guadalupe; Nogueiras, Ruben. 2018. p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1. Nature Communications. 9: 1-16. doi: 10.1038/s41467-018-05711-6
  • Romero-Picó, Amparo; Sanchez-Rebordelo, Estrella; Imbernon, Monica; Gonzalez-Touceda, David; Folgueira, Cintia; Senra, Ana; Fernø, Johan; Blouet, Clemence; Cabrera, Roberto; van Gestel, Margriet; Adan, Roger A.; Lopez, Miguel; Maldonado, Rafael; Nogueiras, Rubén; Diéguez, Carlos. 2018. Melanin-Concentrating Hormone acts through hypothalamic kappa opioid system and p70S6K to stimulate acute food intake. Neuropharmacology. 130: 62-70. doi: 10.1016/j.neuropharm.2017.11.040
  • Contreras, Cristina; González-García, Ismael; Seoane-Collazo, Patricia; Martínez-Sánchez, Noelia; Liñares-Pose, Laura; Rial-Pensado, Eva; Fernø, Johan; Tena-Sempere, Manuel; Casals, Núria; Diéguez, Carlos; Nogueiras, Rubén; López, Miguel. 2017. Reduction of hypothalamic endoplasmic reticulum stress activates browning of white fat and ameliorates obesity. Diabetes. 66: 87-99. doi: 10.2337/db15-1547
  • Ejarque, Miriam; Borlaug, Marianne; Vilarrasa, Núria; Martinez-Perez, Bruno; Megía, Ana; Llauradó, Gemma; Helland, Thomas; Gutierrez, Cristina; Serena, Carolina; Folkestad, Oddry H; Nuñez-Roa, Catalina; Roche, Kelly; Casajoana, Ana; Fradera, Rosa; González-Clemente, José Miguel; López, Miguel; Mohn, Arne-Christian; Nedrebø, Bjørn Gunnar; Nogueiras, Rubén; Mellgren, Gunnar; Fernø, Johan; Fernández-Veledo, Sonia; Vendrell, Joan. 2017. Angiopoietin-like protein 8/betatrophin as a new determinant of type 2 diabetes remission after bariatric surgery. Translational Research: The Journal of Laboratory and Clinical Medicine. 184: 35-44.e4. doi: 10.1016/j.trsl.2017.03.001
  • González-García, Ismael; Fernø, Johan; Diéguez, Carlos; Nogueiras, Rubén; López, Miguel. 2017. Hypothalamic Lipids: Key Regulators of Whole Body Energy Balance. Neuroendocrinology. 104: 398-411. doi: 10.1159/000448432
  • Haugstøyl, Martha Eimstad; Fernø, Johan. 2017. GPR55 - en ny reseptor for behandling av metabolsk sykdom? BestPractice Diabetes.
  • Martínez-Sánchez, Noelia; Moreno-Navarrete, José M.; Contreras, Cristina; Rial-Pensado, Eva; Fernø, Johan; Nogueiras, Rubén; Diéguez, Carlos; Fernández-Real, José Manuel; López, Miguel. 2017. Thyroid hormones induce browning of white fat. Journal of Endocrinology. 232: 351-362. doi: 10.1530/JOE-16-0425
  • Porteiro, Begoña; Fondevila, Marcos F.; Delgado, Teresa C.; Iglesias, Cristina; Imbernon, Monica; Iruzubieta, Paula; Crespo, Javier; Zabala-Letona, Amaia; Fernø, Johan; González-Terán, Bárbara; Matesanz, Nuria; Hernández-Cosido, Lourdes; Marcos, Miguel; Tovar, Sulay; Vidal, Anxo; Sánchez-Ceinos, Julia; Malagon, Maria M.; Pombo, Celia; Zalvide, Juan; Carracedo, Arkaitz; Buque, Xabier; Dieguez, Carlos; Sabio, Guadalupe; López, Miguel; Aspichueta, Patricia; Martínez-Chantar, María L.; Nogueiras, Ruben. 2017. Hepatic p63 regulates steatosis via IKK?/ER stress. Nature Communications. 8:15111: 1-19. doi: 10.1038/ncomms15111
  • Tuduri, Eva; Imbernon, Monica; Hernández-Bautista, Rene Javier; Tojo, Marta; Fernø, Johan; Diéguez, Carlos; Nogueiras, Rubén. 2017. Gpr55: A new promising target for metabolism? Journal of Molecular Endocrinology. 58: R191-R202. doi: 10.1530/JME-16-0253
  • Folgueira, Cintia; Beiroa, Daniel; Callon, Aurelie; Al-Massadi, Omar; Barja-Fernandez, Silvia; Senra, Ana; Fernø, Johan; López, Miguel; Diéguez, Carlos; Casanueva, Felipe F.; Rohner-Jeanrenaud, Françoise; Seoane, Luisa M.; Nogueiras, Ruben. 2016. Uroguanylin action in the brain reduces weight gain in obese mice via different efferent autonomic pathways. Diabetes. 65: 421-432. doi: 10.2337/db15-0889
  • Imbernon, Monica; Sanchez-Rebordelo, Estrella; Romero-Picó, Amparo; Kalló, Imre; Chee, Melissa J.; Porteiro, Begoña; Al-Massadi, Omar; Contreras, Cristina; Fernø, Johan; Senra, Ana; Gallego, Rosalía; Folgueira, Cintia; Seoane, Luisa M.; van Gestel, Margriet; Adan, Roger A.; Liposits, Zsolt; Diéguez, Carlos; López, Miguel; Nogueiras, Rubén. 2016. Hypothalamic kappa opioid receptor mediates both diet-induced and melanin concentrating hormone–induced liver damage through inflammation and endoplasmic reticulum stress. Hepatology. 64: 1086-1104. doi: 10.1002/hep.28716
  • Lage, Ricardo; Fernø, Johan; Nogueiras, Rubén; Diéguez, Carlos; López, Miguel. 2016. Contribution of adaptive thermogenesis to the hypothalamic regulation of energy balance. Biochemical Journal. 473: 4063-4082. doi: 10.1042/BCJ20160012
  • Steen, Vidar Martin; Skrede, Silje; Polushina, Tatiana; López, Miguel; Andreassen, Ole Andreas; Fernø, Johan; Le Hellard, Stephanie. 2016. Genetic evidence for a role of the SREBP transcription system and lipid biosynthesis in schizophrenia and antipsychotic treatment. European Neuropsychopharmacology. 27: 589-598. doi: 10.1016/j.euroneuro.2016.07.011
  • Tuduri, Eva; Beiroa, Daniel; Stegbauer, Johannes; Fernø, Johan; López, Miguel; Diéguez, Carlos; Nogueiras, Rubén. 2016. Acute stimulation of brain mu opioid receptors inhibits glucose-stimulated insulin secretion via sympathetic innervation. Neuropharmacology. 110: 322-332. doi: 10.1016/j.neuropharm.2016.08.005
  • Contreras, Cristina; Gonzalez, Francisco; Fernø, Johan; Diéguez, Carlos; Rahmouni, Kamal; Nogueiras, Rubén; López, Miguel. 2015. The brain and brown fat. Annals of Medicine. 47: 150-168. doi: 10.3109/07853890.2014.919727
  • Fernø, Johan; Ersland, Kari Merete; Duus, Inger Hødnebø; González-García, Ismael; FOSSAN, KJELL OVE; Berge, Rolf Kristian; Steen, Vidar Martin; Skrede, Silje. 2015. Olanzapine depot exposure in male rats: Dose-dependent lipogenic effects without concomitant weight gain. European Neuropsychopharmacology. 25: 923-932. doi: 10.1016/j.euroneuro.2015.03.002
  • Fernø, Johan; Señaris, Rosa; Diéguez, Carlos; Tena-Sempere, Manuel; López, Miguel. 2015. Orexins (hypocretins) and energy balance: More than feeding. Molecular and Cellular Endocrinology. 418: 17-26. doi: 10.1016/j.mce.2015.07.022
  • Lage, Ricardo; Parisi, Claudia; Seoane-Collazo, Patricia; Fernø, Johan; Mazza, Roberta; Bosch, Fátima; Seoane, Luisa M.; Nogueiras, Rubén; Diéguez, Carlos; Quarta, Carmelo; López, Miguel. 2015. Lack of hypophagia in CB1 null mice is associated to decreased Hypothalamic POMC and CART. International Journal of Neuropsychopharmacology. 18: 1-6. doi: 10.1093/ijnp/pyv011
  • Martínez De Morentin, Pablo Blanco; Lage, Ricardo; Gonzalez-Garcia, Ismael; Ruiz-Pino, Francisco; Martins, Luis; Fernandez-Mallo, Diana; Gallego, Rosalía; Fernø, Johan; Senaris, Rosa; Saha, Asish K.; Tovar, Sulay; Diéguez, Carlos; Nogueiras, Ruben; Tena-Sempere, Manuel; Lopez, Miguel. 2015. Pregnancy induces resistance to the anorectic effect of hypothalamic malonyl-COA and the thermogenic effect of hypothalamic AMPK inhibition in female rats. Endocrinology. 156: 947-960. doi: 10.1210/en.2014-1611
  • Massadi, Omar Al; López, Miguel; Fernø, Johan; Diéguez, Carlos; Nogueiras, Rubén. 2015. What is the real relevance of endogenous ghrelin? Peptides. 70: 1-6. doi: 10.1016/j.peptides.2015.04.027
  • Seoane-Collazo, Patricia; Fernø, Johan; Gonzalez, Francisco; Diéguez, Carlos; Leis, Rosaura; Nogueiras, Ruben; López, Miguel. 2015. Hypothalamic-autonomic control of energy homeostasis. Endocrine (Basingstoke). 50: 276-291. doi: 10.1007/s12020-015-0658-y
  • Beiroa, Daniel; Imbernon, Monica; Gallego, Rosalía; Senra, Ana; Herranz, Daniel; Villarroya, Francesc; Serrano, Manuel; Fernø, Johan; Salvador, Javier; Escalada, Javier; Diéguez, Carlos; Lopez, Miguel; Frühbeck, Gema; Nogueiras, Ruben. 2014. GLP-1 agonism stimulates brown adipose tissue thermogenesis and browning through hypothalamic AMPK. Diabetes. 63: 3346-3358. doi: 10.2337/db14-0302
  • Martínez De Morentin, Pablo Blanco; Martinez-Sánchez, Noelia; Roa, Juan; Fernø, Johan; Nogueiras, Rubén S.; Tena-Sempere, Manuel; Diéguez, Carlos; López, Miguel. 2014. Hypothalamic mTOR: the rookie energy sensor. Current molecular medicine. 14: 3-21.
  • Martínez-Sánchez, Noelia; Alvarez, CV; Fernø, Johan; Nogueiras, Ruben; Diéguez, Carlos; López, Miguel. 2014. Hypothalamic effects of thyroid hormones on metabolism. Baillière's Best Practice & Research. Clinical Endocrinology & Metabolism. 28: 703-712. doi: 10.1016/j.beem.2014.04.004
  • Quiñones, Mar; Al-Massadi, Omar; Fernø, Johan; Nogueiras, Ruben. 2014. Cross-talk between SIRT1 and endocrine factors: Effects on energy homeostasis. Molecular and Cellular Endocrinology. 397: 42-50. doi: 10.1016/j.mce.2014.08.002
  • Seoane-Collazo, Patricia; Martínez De Morentin, Pablo Blanco; Fernø, Johan; Diéguez, Carlos; Nogueiras, Rubén S.; López, Miguel. 2014. Nicotine improves obesity and hepatic steatosis and ER stress in diet-induced obese male rats. Endocrinology. 155: 1679-1689. doi: 10.1210/en.2013-1839
  • Skrede, Silje; Martins, Luis; Berge, Rolf Kristian; Steen, Vidar Martin; López, Miguel; Fernø, Johan. 2014. Olanzapine depot formulation in rat: a step forward in modelling antipsychotic-induced metabolic adverse effects. International Journal of Neuropsychopharmacology. 17: 91-104. doi: 10.1017/S1461145713000862
  • Skrede, Silje; Fernø, Johan; Steen, Vidar Martin. 2013. Antipsychotic-induced increase in lipid biosynthesis: activation through inhibition? Journal of Lipid Research. 54: 307-309. doi: 10.1194/jlr.E034736
  • Skrede, Silje; Steen, Vidar Martin; Fernø, Johan. 2013. Antipsychotic-induced increase in lipid biosynthesis: activation through inhibition? Journal of Lipid Research. doi: 10.1194/jlr.E034736
  • Jassim, Goran; Skrede, Silje; Vázquez, Maria Jesús; Vik-Mo, Audun Osland; Lunder, Niclas; Diéguez, Carlos; Vidal-Puig, Antonio; Berge, Rolf Kristian; López, Miguel; Steen, Vidar Martin; Fernø, Johan; Wergedahl, Hege. 2012. Acute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat. Psychopharmacology. 219: 783-794. doi: 10.1007/s00213-011-2397-y
  • Skrede, Silje; Fernø, Johan; Bjørndal, Bodil; Brede, Wenche Rødseth; Bohov, Pavol; Berge, Rolf Kristian; Steen, Vidar Martin. 2012. Lipid-lowering effects of tetradecylthioacetic acid in antipsychotic-exposed, female rats: challenges with long-term treatment. PLOS ONE. 7. 11 pages. doi: 10.1371/journal.pone.0050853
  • Skrede, Silje; Fernø, Johan; Vázquez, Maria Jesús; Fjær, Sveinung; Pavlin, Tina; Lunder, Niclas; Vidal-Puig, Antonio; Diéguez, Carlos; Berge, Rolf Kristian; López, Miguel; Steen, Vidar Martin. 2012. Olanzapine, but not aripiprazole, weight-independently elevates serum triglycerides and activates lipogenic gene expression in female rats. International Journal of Neuropsychopharmacology. 15: 163-179. doi: 10.1017/S1461145711001271
  • de Morentin, Pablo B.Martinez; Whittle, Andrew J.; Fernø, Johan; Nogueiras, Ruben; Diéguez, Carlos; Vidal-Puig, Antonio; López, Miguel. 2012. Nicotine induces negative energy balance through hypothalamic AMP-activated protein kinase. Diabetes. 61: 807-817. doi: 10.2337/db11-1079
  • Fernø, Johan; Skrede, Silje; Vik-Mo, Audun Osland; Jassim, Goran; Le Hellard, Stephanie; Steen, Vidar Martin. 2011. Lipogenic effects of psychotropic drugs: focus on the SREBP system. Frontiers in Bioscience. 16: 49-60. doi: 10.2741/3675
  • Fernø, Johan; Varela, Luis; Skrede, Silje; Vázquez, Maria Jesús; Nogueiras, Ruben; Diéguez, Carlos; Vidal-Puig, Antonio; Steen, Vidar Martin; López, Miguel. 2011. Olanzapine-induced hyperphagia and weight gain associate with crexigenic hypothalamic neuropeptide signaling without concomitant AMPK phosphorylation. PLOS ONE. 6. 9 pages. doi: 10.1371/journal.pone.0020571
  • Jassim, Goran; Fernø, Johan; Theisen, Frank M.; Haberhausen, Michael; Christoforou, Andrea; Håvik, Bjarte; Gebhardt, Stefan; Remschmidt, Helmut; Mehler-Wex, Claudia; Hebebrand, Johannes; Le Hellard, Stephanie; Steen, Vidar Martin. 2011. Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia. Pharmacopsychiatry. 44: 15-20. doi: 10.1055/s-0030-1263174
  • Osland, Teresa Maria; Fernø, Johan; Håvik, Bjarte; Heuch, Ivar; Ruoff, Peter; Lærum, Ole Didrik; Steen, Vidar Martin. 2011. Lithium differentially affects clock gene expression in serum-shocked NIH-3T3 cells. Journal of Psychopharmacology. 25: 924-933. doi: 10.1177/0269881110379508
  • Le Hellard, Stephanie; Mühleisen, Thomas W.; Djurovic, Srdjan; Fernø, Johan; Ouriaghi, Zohra; Mattheisen, Manuel; Vasilescu, Catalina; Ræder, Maria Therese Barøy; Hansen, Thomas; Strohmaier, Jana; Georgi, Alexander; Brockschmidt, Felix F.; Melle, Ingrid; Nenadic, Igor; Sauer, Heinrich; Rietschel, Marcella; Nöthen, Markus M.; Werge, Thomas; Andreassen, Ole Andreas; Cichon, Sven; Steen, Vidar Martin. 2010. Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples. Molecular Psychiatry. 15: 463-472. doi: 10.1038/mp.2008.110
  • Fernø, Johan; Vik-Mo, Audun Osland; Jassim, Goran; Håvik, Bjarte; Berge, Kjetil; Skrede, Silje; Gudbrandsen, Oddrun Anita; Waage, Jo Erling Riise; Lunder, Niclas; Mørk, Sverre; Berge, Rolf Kristian; Jørgensen, Hugo A; Steen, Vidar Martin. 2009. Acute clozapine exposure in vivo induces lipid accumulation and marked sequential changes in the expression of SREBP, PPAR, and LXR target genes in rat liver. Psychopharmacology. 203: 73-84. doi: 10.1007/s00213-008-1370-x
  • Le Hellard, Stephanie; Theisen, Frank M.; Haberhausen, Michael; Ræder, Maria Therese Barøy; Fernø, Johan; Gebhardt, Stefan; Hinney, Anke; Remschmidt, Helmut; Krieg, Jürgen-Christian; Mehler-Wex, Claudia; Nöthen, Markus M.; Hebebrand, Johannes; Steen, Vidar Martin. 2009. Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects? Molecular Psychiatry. 14: 308-317. doi: 10.1038/sj.mp.4002133
  • Vik-Mo, Audun Osland; Fernø, Johan; Skrede, Silje; Steen, Vidar Martin. 2009. Psychotropic drugs up-regulate the expression of cholesterol transport proteins including ApoE in cultured human CNS- and liver cells. BMC Pharmacology. 9. doi: 10.1186/1471-2210-9-10
  • Fernø, Johan; Vik-Mo, Audun Osland; Jassim, Goran; Steen, Vidar Martin. 2008. Effect of clozapine on memory function in the hippocampal lesion model of schizophrenia. International Journal of Neuropsychopharmacology. 11: 261-261.
  • Le Hellard, S; Muhleisen, TW; Djurovic, Srdjan; Fernø, J; Ouriaghi, Z; Mattheisen, M; Vasilescu, C; Raeder, MB; Hansen, T; Strohmaier, J; Georgi, A; Brockschmidt, FF; Melle, I; Nenadic, I; Sauer, H; Rietschel, M; Nothen, MM; Werge, T; Andreassen, Ole Andreas; Cichon, S; Steen, VM. 2008. Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples. Molecular Psychiatry.
  • Le Hellard, Stephanie; Theisen, F.M.; Haberhausen, M; Ræder, Maria Therese Barøy; Fernø, Johan; Gebhardt, S; Hinney, A.; Remschmidt, H.; Krieg, J.C.; Mehler-Wex, C.; Nöthen, Markus M.; Hebebrand, J.; Steen, Vidar Martin. 2008. Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: pertubation of SREBP-controlled lipogenesis in drug-realted metabolic adverse effects? Molecular Psychiatry. 14: 308-317. Published 2008-01-15.
  • Vik-Mo, AO; Birkenæs, Astrid Brate; Fernø, J; Jónsdóttir, Halldóra; Andreassen, Ole Andreas; Steen, VM. 2008. Increased expression of lipid biosynthesis genes in peripheral blood cells of olanzapine-treated patients. International Journal of Neuropsychopharmacology. 11: 679-684.
  • Vik-Mo, Audun Osland; Birkenæs, Astrid B.; Fernø, Johan; Jónsdottir, Halldóra; Andreassen, Ole A.; Steen, Vidar Martin. 2008. Increased expression of lipid biosynthesis genes in peripheral blood cells of olanzapine-treated patients. International Journal of Neuropsychopharmacology. 11: 679-684. doi: 10.1017/S1461145708008468
  • Vik-Mo, Audun Osland; Fernø, Johan; Steen, Vidar Martin. 2008. Differential effects of antipsychotic drugs on ATP-binding cassette type A1 (ABCA1) and apolipoprotein E (ApoE) gene expression in cultured cells. International Journal of Neuropsychopharmacology. 11: 259-259.
  • Vik-Mo, Audun Osland; Birkenæs, Astrid B.; Fernø, Johan; Jónsdottir, Halldóra; Andreassen, Ole Andreas; Steen, Vidar Martin. 2007. Increased expression of lipid biosynthesis genes in peripheral blood cells of olanzapine-treated patients. Nordic Journal of Psychiatry. 61: 501-501. doi: 10.1080/08039480701714778
  • Fernø, Johan; Skrede, Silje; Vik-Mo, Audun Osland; Håvik, Bjarte; Steen, Vidar Martin. 2006. Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: Marked differences between various antipsychotic drugs. BMC Neuroscience. 7. Published 2006-10-20. doi: 10.1186/1471-2202-7-69
  • Ræder, Maria Therese Barøy; Fernø, Johan; Glambek, Marte; Stansberg, Christine; Steen, Vidar Martin. 2006. Antidepressant drugs activate SREBP and up-regulate cholesterol and fatty acid biosynthesis in human glial cells. Neuroscience Letters. 395: 185-190.
  • Ræder, Maria Therese Barøy; Fernø, Johan; Vik-Mo, Audun Osland; Steen, Vidar Martin. 2006. SREBP activation by antipsychotic- and antidepressant-drugs in cultured human liver cells: Relevance for metabolic side-effects? Molecular and Cellular Biochemistry. 289: 167-173. doi: 10.1007/s11010-006-9160-4
  • Vik-Mo, Audun Osland; Fernø, Johan; Ræder, Maria; Steen, Vidar Martin. 2006. Antipsychotic and antidepressive drugs regulate the expression of apolipoprotein E. Nordic Journal of Psychiatry. 60: 338-338.
  • Fernø, Johan; Ræder, Maria Therese Barøy; Vik-Mo, Audun Osland; Skrede, Silje; Glambek, Marte; Tronstad, Karl Johan; Breilid, Harald; Løvlie, Roger; Berge, Rolf Kristian; Stansberg, Christine; Steen, Vidar Martin. 2005. Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action? The Pharmacogenomics Journal. 5: 298-304.
Reports and theses
  • Fernø, Johan. 2007. Lipogenic effects of antipsychotic drugs in cultured cells and in rat. 87 pages.

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