Home
Roger Lille-Langøy's picture

Roger Lille-Langøy

Head Engineer, Environmental toxicology
  • E-mailRoger.Lille-langoy@uib.no
  • Phone+47 55 58 44 98
  • Visitor Address
    Thormøhlensgate 53B, 4th floor
    5006 Bergen
    Room 
    4G17
  • Postal Address
    Postboks 7803
    5020 Bergen
  • 2019. dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA) – HIGHLIGHTS SO FAR.
  • 2019. dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA) – HIGHLIGHTS SO FAR.
  • 2019. Polycyclic aromatic hydrocarbons potentiate vitamin D receptor (Vdr) activation by calcitriol in Atlantic cod (Gadus morhua).
  • 2019. Modulation of neuro-dopamine homeostasis in juvenile female Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances. Environmental Science and Technology. 7036-7044.
  • 2019. In vitro assessment of estrogenic and androgenic effects of bisphenols on Atlantic cod (Gadus morhua).
  • 2019. Environmental contaminants modulate the transcriptional activity of polar bear (Ursus maritimus) and human peroxisome proliferator-activated receptor alpha (PPARA).
  • 2019. Environmental contaminants modulate the transcriptional activity of polar bear (Ursus maritimus) and human peroxisome proliferator-activated receptor alpha (PPARA). Scientific Reports. 1-14.
  • 2019. Contaminant accumulation and biological responses in Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances.
  • 2019. Contaminant accumulation and biological responses in Atlantic cod (Gadus morhua) caged at a capped waste disposal site in Kollevåg, Western Norway. Marine Environmental Research. 39-51.
  • 2019. Biological responses of Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances.
  • 2019. Biological responses of Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons (PAHs) and perfluoroalkyl substances (PFASs) .
  • 2019. Assessment of endocrine disrupting effects of bisphenols in Atlantic cod (Gadus morhua) using luciferase reporter assays and precision-cut liver slices.
  • 2018. dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA).
  • 2018. The nuclear receptor complement of Atlantic cod (Gadus morhua) as potential targets for endocrine disrupting compounds.
  • 2018. Sequence variations in pxr (nr1i2) from Zebrafish (Danio rerio) strains affect nuclear receptor function. Toxicological Sciences. 28-39.
  • 2018. Independent losses of a xenobiotic receptor across teleost evolution. Scientific Reports. 1-13.
  • 2018. Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway .
  • 2018. Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway .
  • 2018. Characterization of the aryl hydrocarbon receptors Ahr1a and Ahr2a in Atlantic cod (Gadus morhua).
  • 2018. Characterization of the aryl hydrocarbon receptors Ahr1a and Ahr2a in Atlantic cod (Gadus morhua).
  • 2018. Characterization of the Atlantic cod (Gadus morhua) Aryl hydrocarbon receptors Ahr1a and Ahr2a.
  • 2018. Characterization of the Atlantic cod (Gadus morhua) Aryl hydrocarbon receptors Ahr1a and Ahr2a.
  • 2018. Characterization of the Atlantic cod (Gadus morhua) Aryl hydrocarbon receptors Ahr1a and Ahr2a.
  • 2018. Assessing the environmental quality of sediments from Split coastal area (Croatia) with a battery of cell-based bioassays. Science of the Total Environment. 1640-1648.
  • 2017. dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua).
  • 2017. dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua) - WP8: biomarkers and xenosensors.
  • 2017. dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua) - WP8: biomarkers and xenosensors.
  • 2017. dCod 1.0 decoding the systems toxicology of Atlantic cod.
  • 2017. Using precision-cut liver slices (PCLS) and luciferase reporter gene assays to characterise the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua).
  • 2017. Using precision-cut liver slices (PCLS) and luciferase reporter gene assays to characterise the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua).
  • 2017. Using precision-cut liver slices (PCLS) and luciferase reporter gene assays to characterise the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua).
  • 2017. Studying estrogenic effects of environmental pollutants by using the Atlantic cod (Gadus morhua) estrogen receptor α and a reporter gene assay.
  • 2017. Peroxisome proliferator-activated receptors (PPARs) as tools for studying effects of contaminants on the Atlantic cod (Gadus morhua) lipid metabolism.
  • 2017. PRECISION-CUT LIVER SLICES (PCLS) FOR TOXICOGENOMIC STUDIES IN ATLANTIC COD (Gadus morhua): THE dCOD 1.0 PROJECT.
  • 2017. Nuclear receptor targets for environmental pollutants. Modulation of transcriptional activity of pregnane x receptor and peroxisome proliferator-activated receptor gamma in polar bears and zebrafish.
  • 2017. Multiple-stressor effects in an apex predator: combined influence of pollutants and sea ice decline on lipid metabolism in polar bears. Scientific Reports. 12 pages.
  • 2017. Ecotoxicological responses in Atlantic cod (Gadus morhua) following caging near a previously capped waste disposal site in Kollevågen, Askøy, Norway .
  • 2017. Ecotoxicological responses in Atlantic cod (Gadus morhua) following caging near a previously capped waste disposal site in Kollevågen, Askøy, Norway .
  • 2017. Ecotoxicological responses in Atlantic cod (Gadus morhua) following caging near a previously capped waste disposal site in Kollevågen, Askøy, Norway .
  • 2017. Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway .
  • 2017. CHARACTERIZATION OF THE ARYL HYDROCARBON RECEPTORS AHR1B AND AHR2 IN ATLANTIC COD (GADUS MORHUA).
  • 2016. Using precision-cut liver slices (PCLS) and luciferase reporter gene assay to characterize the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua).
  • 2016. Peroxisome proliferator-activated receptors (PPARs) as tools to study effects of contaminants on the Atlantic cod (Gadus morhua) lipid metabolism.
  • 2016. Environmental chemicals modulate polar bear (Ursus maritimus) Peroxisome Proliferator-Activated Receptor Gamma (PPARG) and adipogenesis in vitro. Environmental Science and Technology. 10708-10720.
  • 2016. Chemical warfare in the marine environment: genomic survey of the Atlantic cod (Gadus morhua) defensome reveals the absence of an important xenosensor.
  • 2016. Assessment of the environmental quality of coastal sediments by using a combination of in vitro bioassays. Marine Pollution Bulletin. 53-61.
  • 2015. Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently. Toxicology and Applied Pharmacology. 54-64.
  • 2013. Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in Zebrafish (Danio rerio). Aquatic Toxicology. 447-457.
  • 2010. Nuclear receptor targets for endocrine disrupting compounds. Comparative Biochemistry and Physiology A. S30-S30.
  • 2005. Methylococcus capsulatus (Bath); The secretion mechanism and the copper binding ability of the MopE protein.

More information in national current research information system (CRIStin)

 

Publications:

Multiple-stressor effects in an apex predator: combined influence of pollutants and sea ice decline on lipid metabolism in polar bears.

Tartu S, Lille-Langøy R, Størseth TR, Bourgeon S, Brunsvik A, Aars J, Goksøyr A, Jenssen BM, Polder A, Thiemann GW, Torget V, Routti H.

Sci Rep. 2017 Nov 28;7(1):16487. doi: 10.1038/s41598-017-16820-5.

PMID: 29184161 Free Article

 

Assessing the environmental quality of sediments from Split coastal area (Croatia) with a battery of cell-based bioassays.

Blanco M, Pérez-Albaladejo E, Piña B, Kušpilić G, Milun V, Lille-Langøy R, Karlsen OA, Goksøyr A, Porte C.

Sci Total Environ. 2017 Oct 23. pii: S0048-9697(17)32758-4. doi: 10.1016/j.scitotenv.2017.10.055. [Epub ahead of print]

PMID: 29074243

 

Environmental Chemicals Modulate Polar Bear (Ursus maritimus) Peroxisome Proliferator-Activated Receptor Gamma (PPARG) and Adipogenesis in Vitro.

Routti H, Lille-Langøy R, Berg MK, Fink T, Harju M, Kristiansen K, Rostkowski P, Rusten M, Sylte I, Øygarden L, Goksøyr A.

Environ Sci Technol. 2016 Oct 4;50(19):10708-10720. Epub 2016 Sep 19.

PMID: 27602593

 

Assessment of the environmental quality of coastal sediments by using a combination of in vitro bioassays.

Pérez-Albaladejo E, Rizzi J, Fernandes D, Lille-Langøy R, Karlsen OA, Goksøyr A, Oros A, Spagnoli F, Porte C.

Mar Pollut Bull. 2016 Jul 15;108(1-2):53-61. doi: 10.1016/j.marpolbul.2016.04.063. Epub 2016 May 17.

PMID: 27207027

 

Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently.

Lille-Langøy R, Goldstone JV, Rusten M, Milnes MR, Male R, Stegeman JJ, Blumberg B, Goksøyr A.

Toxicol Appl Pharmacol. 2015 Apr 1;284(1):54-64. doi: 10.1016/j.taap.2015.02.001. Epub 2015 Feb 10.

PMID: 25680588 Free PMC Article

 

Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in zebrafish (Danio rerio).

Bainy AC, Kubota A, Goldstone JV, Lille-Langøy R, Karchner SI, Celander MC, Hahn ME, Goksøyr A, Stegeman JJ.

Aquat Toxicol. 2013 Oct 15;142-143:447-57. doi: 10.1016/j.aquatox.2013.09.014. Epub 2013 Sep 20.

PMID: 24121122 Free PMC Article

 

Research groups