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Rolf Bjerkvig's picture

Rolf Bjerkvig

Professor
The Department of Biomedicine
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  • E-mailRolf.Bjerkvig@uib.no
  • Phone+47 55 58 63 52+47 951 18 268
  • Visitor Address
    Jonas Lies vei 91
  • Postal Address
    Postboks 7804
    5020 Bergen

Rolf Bjerkvig (f. 1953) is Professor for cell biology and has since the ealy 80s worked in experimental cancer biology.

Bjerkvig is Director of the Kristian Gerhard Jebsen Brain Tumor Research Center, located at the Department of Biomedicine. He is director of the Oncology Department at the Luxembourg Institute of Health, and has established the NORLUX Neuro-Oncology network.

Dr Bjerkvig receives major grants from the Norwegian Research Council, The Norwegian Cancer Society and the European Commission. He is on the editorial board on several international journals and is sitting in several national as well as international funding committees for cancer research in Europe. He has published more than 200 articles in scientific literature and has received a number of research prizes for his work. In 2015, Bjerkvig was awarded the King Olav V Research Prize in Cancer Research.

OD1ANA - Anatomy

MEDOD1, MEDOD2

MEIBM900

FARM260 - Molecular cell biology

BMED330 - intercellular communication

BMED331 - tumor biology

  • Han, Mingzhi; Xu, Ran; Wang, Shuai; Yang, Ning; Ni, Shilei; Zhang, Qing; Xu, Yangyang; Zhang, Xin; Zhang, Chao; Wei, Yuzhen; Ji, Jianxiong; Huang, Bin; Zhang, Di; Chen, Anjing; Li, Wenjie; Bjerkvig, Rolf; Li, Xingang; Wang, Jian. 2018. Six-Transmembrane Epithelial Antigen of Prostate 3 Predicts Poor Prognosis and Promotes Glioblastoma Growth and Invasion. Neoplasia. 20: 543-554. doi: 10.1016/j.neo.2018.04.002
  • Johannessen, Tor-Christian Aase; Hasan-Olive, Md Mahdi; Zhu, Huaiyang; Denisova, Oxana V.; Grudic, Amra; Latif, Md Abdul; Sdik Saed, Halala; Varughese, Jobin K.; Røsland, Gro Vatne; Yang, Ning; Sundstrøm, Terje; Nordal, Anne Birgitte Thomas; Tronstad, Karl Johan; Wang, Jian; Lund-Johansen, Morten; Simonsen, Anne; Janji, Bassam; Westermarck, Jutta; Bjerkvig, Rolf; Prestegarden, Lars. 2018. Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide. International Journal of Cancer. Published 2018-10-05. doi: 10.1002/ijc.31912
  • Wang, Jiwei; Qi, Qichao; Zhou, Wenjing; Feng, Zichao; Huang, Bin; Chen, Anjing; Zhang, Di; Li, Wenjie; Zhang, Qing; Jiang, Zheng; Bjerkvig, Rolf; Prestegarden, Lars; Thorsen, Frits; Wang, Xinyu; Li, Xingang; Wang, Jian. 2018. Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. Autophagy. 14: 2007-2022. doi: 10.1080/15548627.2018.1501133
  • Zhou, Wenjing; Wang, Jiwei; Qi, Qichao; Feng, Zichao; Huang, Bin; Chen, Anjing; Zhang, Di; Li, Wenjie; Zhang, Qing; Bjerkvig, Rolf; Li, Xingang; Wang, Jian. 2018. Matrine induces senescence of human glioblastoma cells through suppression of the IGF1/PI3K/AKT/p27 signaling pathway. Cancer Medicine. 7: 4729-4748. doi: 10.1002/cam4.1720
  • Atzori, Maria Grazia; Tentori, Lucio; Ruffini, Federica; Ceci, Claudia; Lisi, Lucia; Bonanno, Elena; Scimeca, Manuel; Eskilsson, Eskil; Daubon, Thomas; Miletic, Hrvoje; Ricci Vitiani, Lucia; Pallini, Roberto; Navarra, Pierluigi; Bjerkvig, Rolf; D'Atri, Stefania; Lacal, Pedro Miguel; Graziani, Grazia. 2017. The anti-vascular endothelial growth factor receptor-1 monoclonal antibody D16F7 inhibits invasiveness of human glioblastoma and glioblastoma stem cells. Journal of Experimental & Clinical Cancer Research. 36:106: 1-15. doi: 10.1186/s13046-017-0577-2
  • Boyé, Kevin; Pujol, Nadège; D Alves, Isabel; Chen, Ya-Ping; Daubon, Thomas; Lee, Yi-Zong; Dedieu, Stephane; Constantin, Marion; Bello, Lorenzo; Rossi, Marco; Bjerkvig, Rolf; Sue, Shih-Che; Bikfalvi, Andreas; Billottet, Clotilde. 2017. The role of CXCR3/LRP1 cross-talk in the invasion of primary brain tumors. Nature Communications. 8:1571: 1-20. doi: 10.1038/s41467-017-01686-y
  • Eskilsson, Eskil; Røsland, Gro Vatne; Solecki, Gergely; Wang, Qianghu; Harter, Patrick N.; Graziani, Grazia; Verhaak, Roel G; Winkler, Frank; Bjerkvig, Rolf; Miletic, Hrvoje. 2017. EGFR heterogeneity and implications for therapeutic intervention in glioblastoma. Neuro-Oncology. 20: 743-752. doi: 10.1093/neuonc/nox191
  • Fack, Fred; Tardito, Saverio; Hochart, Guillaume; Oudin, Anaïs; Zheng, Liang; Fritah, Sabrina; Golebiewska, Anna; Nazarov, Petr; Bernard, Amandine; Hau, Ann-Christin; Keunen, Olivier; Leenders, William P.J.; Lund-Johansen, Morten; Stauber, Jonathan; Gottlieb, Eyal; Bjerkvig, Rolf; Niclou, Simone Pierrette. 2017. Altered metabolic landscape in IDH‐mutant gliomas affects phospholipid, energy, and oxidative stress pathways. EMBO Molecular Medicine. 9: 1681-1695. doi: 10.15252/emmm.201707729
  • Obad, Nina; Espedal, Heidi; Jirík, Radovan; Sakariassen, Per Øystein; Rygh, Cecilie Brekke; Lund-Johansen, Morten; Taxt, Torfinn; Niclou, Simone Pierrette; Bjerkvig, Rolf; Keunen, Olivier. 2017. Lack of functional normalisation of blood vessels following anti-angiogenic therapy in glioblastoma. Journal of Cerebral Blood Flow and Metabolism. doi: 10.1177/0271678X17714656
  • Zhang, Xin; Xu, Ran; Zhang, Chao; Xu, Yangyang; Han, Mingzhi; Huang, Bin; Chen, Anjing; Qiu, Chen; Thorsen, Frits; Prestegarden, Lars; Bjerkvig, Rolf; Wang, Jian; Li, Xingang. 2017. Trifluoperazine, a novel autophagy inhibitor, increases radiosensitivity in glioblastoma by impairing homologous recombination. Journal of Experimental & Clinical Cancer Research. 36:118: 1-13. doi: 10.1186/s13046-017-0588-z

More information in national current research information system (CRIStin)

1987: Dr. philos. The Gade Institute of Pathology, University of Bergen
1981: M.Sc. Immunology, University of San Francisco, 1981.

Fields of competence 
Cancer research
Human physiology